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Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models.
Clin Cancer Res. 2023 Apr 14;29(8):1631-1642. doi: 10.1158/1078-0432.CCR-22-2977.
Clin Cancer Res. 2023.
PMID: 36689546
Free PMC article.
Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types.
Pilié PG, Giuliani V, Wang WL, McGrail DJ, Bristow CA, Ngoi NYL, Kyewalabye K, Wani KM, Le H, Campbell E, Sanchez NS, Yang D, Gheeya JS, Goswamy RV, Holla V, Shaw KR, Meric-Bernstam F, Liu CY, Ma X, Feng N, Machado AA, Bardenhagen JP, Vellano CP, Marszalek JR, Rajendra E, Piscitello D, Johnson TI, Likhatcheva M, Elinati E, Majithiya J, Neves J, Grinkevich V, Ranzani M, Luzarraga MR, Boursier M, Armstrong L, Geo L, Lillo G, Tse WY, Lazar AJ, Kopetz SE, Geck Do MK, Lively S, Johnson MG, Robinson HMR, Smith GCM, Carroll CL, Di Francesco ME, Jones P, Heffernan TP, Yap TA.
Pilié PG, et al. Among authors: piscitello d.
Clin Cancer Res. 2024 May 15;30(10):2121-2139. doi: 10.1158/1078-0432.CCR-23-1763.
Clin Cancer Res. 2024.
PMID: 38416404
Free PMC article.
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AKT overactivation can suppress DNA repair via p70S6 kinase-dependent downregulation of MRE11.
Piscitello D, Varshney D, Lilla S, Vizioli MG, Reid C, Gorbunova V, Seluanov A, Gillespie DA, Adams PD.
Piscitello D, et al.
Oncogene. 2018 Jan 25;37(4):427-438. doi: 10.1038/onc.2017.340. Epub 2017 Oct 2.
Oncogene. 2018.
PMID: 28967905
Free PMC article.
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Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, Riethman H, Wu H, Schotta G, Garcia BA, Neretti N, Baird DM, Berger SL, Adams PD.
Nelson DM, et al. Among authors: piscitello d.
Genome Biol. 2016 Jul 25;17(1):158. doi: 10.1186/s13059-016-1017-x.
Genome Biol. 2016.
PMID: 27457071
Free PMC article.
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KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage.
Gong EY, Smits VAJ, Fumagallo F, Piscitello D, Morrice N, Freire R, Gillespie DA.
Gong EY, et al. Among authors: piscitello d.
Sci Rep. 2015 Jun 3;5:10856. doi: 10.1038/srep10856.
Sci Rep. 2015.
PMID: 26039276
Free PMC article.
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Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death.
Lentini L, Piscitello D, Veneziano L, Di Leonardo A.
Lentini L, et al. Among authors: piscitello d.
Cell Biol Int. 2014 Aug;38(8):933-41. doi: 10.1002/cbin.10277. Epub 2014 Apr 10.
Cell Biol Int. 2014.
PMID: 24687487
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Experimental procedures comparing the activity of different Taq polymerases.
Spitaleri S, Piscitello D, Di Martino D, Saravo L.
Spitaleri S, et al. Among authors: piscitello d.
Forensic Sci Int. 2004 Dec 2;146 Suppl:S167-9. doi: 10.1016/j.forsciint.2004.09.051.
Forensic Sci Int. 2004.
PMID: 15639568
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