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Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.
Kim H, Villareal LB, Liu Z, Haneef M, Falcon DM, Martin DR, Lee HJ, Dame MK, Attili D, Chen Y, Varani J, Spence JR, Kovbasnjuk O, Colacino JA, Lyssiotis CA, Lin HC, Shah YM, Xue X. Kim H, et al. Among authors: lyssiotis ca. Adv Sci (Weinh). 2023 Apr;10(10):e2207693. doi: 10.1002/advs.202207693. Epub 2023 Jan 26. Adv Sci (Weinh). 2023. PMID: 36703617 Free PMC article.
Menin regulates the serine biosynthetic pathway in Ewing sarcoma.
Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER. Svoboda LK, et al. Among authors: lyssiotis ca. J Pathol. 2018 Jul;245(3):324-336. doi: 10.1002/path.5085. Epub 2018 May 28. J Pathol. 2018. PMID: 29672864 Free PMC article.
Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress.
Devenport SN, Singhal R, Radyk MD, Taranto JG, Kerk SA, Chen B, Goyert JW, Jain C, Das NK, Oravecz-Wilson K, Zhang L, Greenson JK, Chen YE, Soleimanpour SA, Reddy P, Lyssiotis CA, Shah YM. Devenport SN, et al. Among authors: lyssiotis ca. JCI Insight. 2021 Jun 17;6(14):e138835. doi: 10.1172/jci.insight.138835. JCI Insight. 2021. PMID: 34138755 Free PMC article.
Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.
Schwartz AJ, Goyert JW, Solanki S, Kerk SA, Chen B, Castillo C, Hsu PP, Do BT, Singhal R, Dame MK, Lee HJ, Spence JR, Lakhal-Littleton S, Vander Heiden MG, Lyssiotis CA, Xue X, Shah YM. Schwartz AJ, et al. Among authors: lyssiotis ca. Nat Metab. 2021 Jul;3(7):969-982. doi: 10.1038/s42255-021-00406-7. Epub 2021 Jun 21. Nat Metab. 2021. PMID: 34155415 Free PMC article.
196 results