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Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.
Kim H, Villareal LB, Liu Z, Haneef M, Falcon DM, Martin DR, Lee HJ, Dame MK, Attili D, Chen Y, Varani J, Spence JR, Kovbasnjuk O, Colacino JA, Lyssiotis CA, Lin HC, Shah YM, Xue X. Kim H, et al. Among authors: spence jr. Adv Sci (Weinh). 2023 Apr;10(10):e2207693. doi: 10.1002/advs.202207693. Epub 2023 Jan 26. Adv Sci (Weinh). 2023. PMID: 36703617 Free PMC article.
Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer.
Xue X, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Győrffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM. Xue X, et al. Among authors: spence jr. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. doi: 10.1073/pnas.1712946114. Epub 2017 Oct 23. Proc Natl Acad Sci U S A. 2017. PMID: 29078383 Free PMC article.
Identification, isolation and characterization of human LGR5-positive colon adenoma cells.
Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA. Dame MK, et al. Among authors: spence jr. Development. 2018 Mar 14;145(6):dev153049. doi: 10.1242/dev.153049. Development. 2018. PMID: 29467240 Free PMC article.
A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture.
Tsai YH, Czerwinski M, Wu A, Dame MK, Attili D, Hill E, Colacino JA, Nowacki LM, Shroyer NF, Higgins PDR, Kao JY, Spence JR. Tsai YH, et al. Among authors: spence jr. Cell Mol Gastroenterol Hepatol. 2018 May 30;6(2):218-222.e7. doi: 10.1016/j.jcmgh.2018.04.008. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 30105282 Free PMC article. No abstract available.
Astrovirus replication in human intestinal enteroids reveals multi-cellular tropism and an intricate host innate immune landscape.
Kolawole AO, Mirabelli C, Hill DR, Svoboda SA, Janowski AB, Passalacqua KD, Rodriguez BN, Dame MK, Freiden P, Berger RP, Vu DL, Hosmillo M, O'Riordan MXD, Schultz-Cherry S, Guix S, Spence JR, Wang D, Wobus CE. Kolawole AO, et al. Among authors: spence jr. PLoS Pathog. 2019 Oct 31;15(10):e1008057. doi: 10.1371/journal.ppat.1008057. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31671153 Free PMC article.
Microbial Metabolite Signaling Is Required for Systemic Iron Homeostasis.
Das NK, Schwartz AJ, Barthel G, Inohara N, Liu Q, Sankar A, Hill DR, Ma X, Lamberg O, Schnizlein MK, Arqués JL, Spence JR, Nunez G, Patterson AD, Sun D, Young VB, Shah YM. Das NK, et al. Among authors: spence jr. Cell Metab. 2020 Jan 7;31(1):115-130.e6. doi: 10.1016/j.cmet.2019.10.005. Epub 2019 Nov 7. Cell Metab. 2020. PMID: 31708445 Free PMC article.
Enteroendocrine Progenitor Cell-Enriched miR-7 Regulates Intestinal Epithelial Proliferation in an Xiap-Dependent Manner.
Singh AP, Hung YH, Shanahan MT, Kanke M, Bonfini A, Dame MK, Biraud M, Peck BCE, Oyesola OO, Freund JM, Cubitt RL, Curry EG, Gonzalez LM, Bewick GA, Tait-Wojno ED, Kurpios NA, Ding S, Spence JR, Dekaney CM, Buchon N, Sethupathy P. Singh AP, et al. Among authors: spence jr. Cell Mol Gastroenterol Hepatol. 2020;9(3):447-464. doi: 10.1016/j.jcmgh.2019.11.001. Epub 2019 Nov 19. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31756561 Free PMC article.
Differentiation of human colon tissue in culture: Effects of calcium on trans-epithelial electrical resistance and tissue cohesive properties.
McClintock SD, Attili D, Dame MK, Richter A, Silvestri SS, Berner MM, Bohm MS, Karpoff K, McCarthy CL, Spence JR, Varani J, Aslam MN. McClintock SD, et al. Among authors: spence jr. PLoS One. 2020 Mar 5;15(3):e0222058. doi: 10.1371/journal.pone.0222058. eCollection 2020. PLoS One. 2020. PMID: 32134920 Free PMC article.
212 results