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Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.
Mankan AK, Schmidt T, Chauhan D, Goldeck M, Höning K, Gaidt M, Kubarenko AV, Andreeva L, Hopfner KP, Hornung V. Mankan AK, et al. Among authors: hornung v. EMBO J. 2014 Dec 17;33(24):2937-46. doi: 10.15252/embj.201488726. Epub 2014 Nov 25. EMBO J. 2014. PMID: 25425575 Free PMC article.
Mitochondrial dsRNA: A New DAMP for MDA5.
Linder A, Hornung V. Linder A, et al. Among authors: hornung v. Dev Cell. 2018 Sep 10;46(5):530-532. doi: 10.1016/j.devcel.2018.08.019. Dev Cell. 2018. PMID: 30205036 Free article.
TLR8 Is a Sensor of RNase T2 Degradation Products.
Greulich W, Wagner M, Gaidt MM, Stafford C, Cheng Y, Linder A, Carell T, Hornung V. Greulich W, et al. Among authors: hornung v. Cell. 2019 Nov 27;179(6):1264-1275.e13. doi: 10.1016/j.cell.2019.11.001. Cell. 2019. PMID: 31778653 Free PMC article.
CARD8 inflammasome activation triggers pyroptosis in human T cells.
Linder A, Bauernfried S, Cheng Y, Albanese M, Jung C, Keppler OT, Hornung V. Linder A, et al. Among authors: hornung v. EMBO J. 2020 Oct 1;39(19):e105071. doi: 10.15252/embj.2020105071. Epub 2020 Aug 25. EMBO J. 2020. PMID: 32840892 Free PMC article.
C-tag TNF: a reporter system to study TNF shedding.
Pinci F, Gaidt MM, Jung C, Kuut G, Jackson MA, Bauernfried S, Hornung V. Pinci F, et al. Among authors: hornung v. J Biol Chem. 2020 Dec 25;295(52):18065-18075. doi: 10.1074/jbc.RA120.015248. Epub 2020 Oct 20. J Biol Chem. 2020. PMID: 33082141 Free PMC article.
Irgm2 and Gate-16 put a break on caspase-11 activation.
Linder A, Hornung V. Linder A, et al. Among authors: hornung v. EMBO Rep. 2020 Nov 5;21(11):e51787. doi: 10.15252/embr.202051787. Epub 2020 Nov 1. EMBO Rep. 2020. PMID: 33135287 Free PMC article.
Inflammasomes in T cells.
Linder A, Hornung V. Linder A, et al. Among authors: hornung v. J Mol Biol. 2022 Feb 28;434(4):167275. doi: 10.1016/j.jmb.2021.167275. Epub 2021 Sep 29. J Mol Biol. 2022. PMID: 34599941 Review.
214 results