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230 results

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Page 1
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade.
Conche C, Finkelmeier F, Pešić M, Nicolas AM, Böttger TW, Kennel KB, Denk D, Ceteci F, Mohs K, Engel E, Canli Ö, Dabiri Y, Peiffer KH, Zeuzem S, Salinas G, Longerich T, Yang H, Greten FR. Conche C, et al. Among authors: longerich t. Gut. 2023 Sep;72(9):1774-1782. doi: 10.1136/gutjnl-2022-327909. Epub 2023 Jan 27. Gut. 2023. PMID: 36707233 Free PMC article.
Reduced efficacy of the Plk1 inhibitor BI 2536 on the progression of hepatocellular carcinoma due to low intratumoral drug levels.
Haupenthal J, Bihrer V, Korkusuz H, Kollmar O, Schmithals C, Kriener S, Engels K, Pleli T, Benz A, Canamero M, Longerich T, Kronenberger B, Richter S, Waidmann O, Vogl TJ, Zeuzem S, Piiper A. Haupenthal J, et al. Among authors: longerich t. Neoplasia. 2012 May;14(5):410-9. doi: 10.1596/neo.111366. Neoplasia. 2012. PMID: 22745587 Free PMC article.
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.
Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, Kang TW, Yevsa T, Heinzmann F, Hoenicke L, Hohmeyer A, Potapova A, Rittelmeier I, Jarek M, Geffers R, Scharfe M, Klawonn F, Schirmacher P, Malek NP, Ott M, Nordheim A, Vogel A, Manns MP, Zender L. Wuestefeld T, et al. Among authors: longerich t. Cell. 2013 Apr 11;153(2):389-401. doi: 10.1016/j.cell.2013.03.026. Cell. 2013. PMID: 23582328 Free article.
RSPO2 gene rearrangement: a powerful driver of β-catenin activation in liver tumours.
Longerich T, Endris V, Neumann O, Rempel E, Kirchner M, Abadi Z, Uhrig S, Kriegsmann M, Weiss KH, Breuhahn K, Mehrabi A, Weber TF, Wilkens L, Straub BK, Rosenwald A, Schulze F, Brors B, Froehling S, Pellegrino R, Budczies J, Schirmacher P, Stenzinger A. Longerich T, et al. Gut. 2019 Jul;68(7):1287-1296. doi: 10.1136/gutjnl-2018-317632. Epub 2019 Feb 2. Gut. 2019. PMID: 30901310
p21 promotes sustained liver regeneration and hepatocarcinogenesis in chronic cholestatic liver injury.
Marhenke S, Buitrago-Molina LE, Endig J, Orlik J, Schweitzer N, Klett S, Longerich T, Geffers R, Sánchez Muñoz A, Dorrell C, Katz SF, Lechel A, Weng H, Krech T, Lehmann U, Dooley S, Rudolph KL, Manns MP, Vogel A. Marhenke S, et al. Among authors: longerich t. Gut. 2014 Sep;63(9):1501-12. doi: 10.1136/gutjnl-2013-304829. Epub 2013 Oct 3. Gut. 2014. PMID: 24092862
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
Rudalska R, Dauch D, Longerich T, McJunkin K, Wuestefeld T, Kang TW, Hohmeyer A, Pesic M, Leibold J, von Thun A, Schirmacher P, Zuber J, Weiss KH, Powers S, Malek NP, Eilers M, Sipos B, Lowe SW, Geffers R, Laufer S, Zender L. Rudalska R, et al. Among authors: longerich t. Nat Med. 2014 Oct;20(10):1138-46. doi: 10.1038/nm.3679. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216638 Free PMC article.
Non-invasive diagnosis of hepatocellular carcinoma revisited.
Mueller C, Waldburger N, Stampfl U, Kauczor HU, Schirmacher P, Sommer CM, Longerich T. Mueller C, et al. Among authors: longerich t. Gut. 2018 May;67(5):991-993. doi: 10.1136/gutjnl-2017-314981. Epub 2017 Sep 12. Gut. 2018. PMID: 28899984 No abstract available.
Tax1BP1 limits hepatic inflammation and reduces experimental hepatocarcinogenesis.
Waidmann O, Pleli T, Weigert A, Imelmann E, Kakoschky B, Schmithals C, Döring C, Frank M, Longerich T, Köberle V, Hansmann ML, Brüne B, Zeuzem S, Piiper A, Dikic I. Waidmann O, et al. Among authors: longerich t. Sci Rep. 2020 Oct 1;10(1):16264. doi: 10.1038/s41598-020-73387-4. Sci Rep. 2020. PMID: 33004985 Free PMC article.
230 results