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Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial.
Hamer MJ, Houser KV, Hofstetter AR, Ortega-Villa AM, Lee C, Preston A, Augustine B, Andrews C, Yamshchikov GV, Hickman S, Schech S, Hutter JN, Scott PT, Waterman PE, Amare MF, Kioko V, Storme C, Modjarrad K, McCauley MD, Robb ML, Gaudinski MR, Gordon IJ, Holman LA, Widge AT, Strom L, Happe M, Cox JH, Vazquez S, Stanley DA, Murray T, Dulan CNM, Hunegnaw R, Narpala SR, Swanson PA 2nd, Basappa M, Thillainathan J, Padilla M, Flach B, O'Connell S, Trofymenko O, Morgan P, Coates EE, Gall JG, McDermott AB, Koup RA, Mascola JR, Ploquin A, Sullivan NJ, Ake JA, Ledgerwood JE; RV 507 Study Team. Hamer MJ, et al. Among authors: schech s. Lancet. 2023 Jan 28;401(10373):294-302. doi: 10.1016/S0140-6736(22)02400-X. Lancet. 2023. PMID: 36709074 Free PMC article. Clinical Trial.
Safety, tolerability, and immunogenicity of the Ebola Sudan chimpanzee adenovirus vector vaccine (cAd3-EBO S) in healthy Ugandan adults: a phase 1, open-label, dose-escalation clinical trial.
Mwesigwa B, Houser KV, Hofstetter AR, Ortega-Villa AM, Naluyima P, Kiweewa F, Nakabuye I, Yamshchikov GV, Andrews C, O'Callahan M, Strom L, Schech S, Anne Eller L, Sondergaard EL, Scott PT, Amare MF, Modjarrad K, Wamala A, Tindikahwa A, Musingye E, Nanyondo J, Gaudinski MR, Gordon IJ, Holman LA, Saunders JG, Costner PJM, Mendoza FH, Happe M, Morgan P, Plummer SH, Hickman SP, Vazquez S, Murray T, Cordon J, Dulan CNM, Hunegnaw R, Basappa M, Padilla M, Gajjala SR, Swanson PA 2nd, Lin BC, Coates EE, Gall JG, McDermott AB, Koup RA, Mascola JR, Ploquin A, Sullivan NJ, Kibuuka H, Ake JA, Ledgerwood JE; RV 508 Study Team. Mwesigwa B, et al. Among authors: schech s. Lancet Infect Dis. 2023 Dec;23(12):1408-1417. doi: 10.1016/S1473-3099(23)00344-4. Epub 2023 Aug 3. Lancet Infect Dis. 2023. PMID: 37544326 Clinical Trial.
Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1.
Matavele Chissumba R, Magul C, Macamo R, Monteiro V, Enosse M, Macicame I, Cumbane V, Bhatt N, Viegas E, Imbach M, Eller LA, Polyak CS, Kestens L; RV363 Study Group. Matavele Chissumba R, et al. BMC Immunol. 2022 Mar 14;23(1):12. doi: 10.1186/s12865-022-00487-3. BMC Immunol. 2022. PMID: 35287587 Free PMC article.
Impact of age on CD4 recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study.
Bahemana E, Esber A, Dear N, Ganesan K, Parikh A, Reed D, Maganga L, Khamadi S, Mizinduko M, Lwilla A, Mkondoo D, Mwaisanga G, Somi N, Owouth J, Maswai J, Kiweewa F, Iroezindu M, Ake JA, Crowell TA, Valcour VG, Polyak CS; AFRICOS Study Group. Bahemana E, et al. AIDS Res Ther. 2020 Nov 12;17(1):66. doi: 10.1186/s12981-020-00323-x. AIDS Res Ther. 2020. PMID: 33183355 Free PMC article.
Transient Reductions in Human Immunodeficiency Virus (HIV) Clinic Attendance and Food Security During the Coronavirus Disease 2019 (COVID-19) Pandemic for People Living With HIV in 4 African Countries.
Dear N, Duff E, Esber A, Parikh A, Iroezindu M, Bahemana E, Kibuuka H, Owuoth J, Maswai J, Crowell TA, Ake JA, Polyak CS; AFRICOS Study Group. Dear N, et al. Clin Infect Dis. 2021 Nov 16;73(10):1901-1905. doi: 10.1093/cid/ciab379. Clin Infect Dis. 2021. PMID: 33906235 Free PMC article.
Routine HIV clinic visit adherence in the African Cohort Study.
Dear N, Esber A, Iroezindu M, Bahemana E, Kibuuka H, Maswai J, Owuoth J, Polyak CS, Ake JA, Crowell TA; AFRICOS Study Group. Dear N, et al. AIDS Res Ther. 2022 Jan 7;19(1):1. doi: 10.1186/s12981-021-00425-0. AIDS Res Ther. 2022. PMID: 34996470 Free PMC article.
Epidemiology of Tuberculosis Among People Living With HIV in the African Cohort Study From 2013 to 2021.
Ganesan K, Mwesigwa R, Dear N, Esber AL, Reed D, Kibuuka H, Iroezindu M, Bahemana E, Owuoth J, Singoei V, Maswai J, Parikh AP, Crowell TA, Ake JA, Polyak CS, Shah N, Cavanaugh JS; AFRICOS Study Group; AFRICOS Study Group. Ganesan K, et al. J Acquir Immune Defic Syndr. 2023 Apr 15;92(5):359-369. doi: 10.1097/QAI.0000000000003152. Epub 2023 Jan 3. J Acquir Immune Defic Syndr. 2023. PMID: 36728618 Free PMC article.
30 results