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Gut microbes and the liver circadian clock partition glucose and lipid metabolism.
Frazier K, Manzoor S, Carroll K, DeLeon O, Miyoshi S, Miyoshi J, St George M, Tan A, Chrisler EA, Izumo M, Takahashi JS, Rao MC, Leone VA, Chang EB. Frazier K, et al. Among authors: leone va. J Clin Invest. 2023 Sep 15;133(18):e162515. doi: 10.1172/JCI162515. J Clin Invest. 2023. PMID: 37712426 Free PMC article.
Peptide YY: A Paneth cell antimicrobial peptide that maintains Candida gut commensalism.
Pierre JF, Peters BM, La Torre D, Sidebottom AM, Tao Y, Zhu X, Cham CM, Wang L, Kambal A, Harris KG, Silva JF, Zaborina O, Alverdy JC, Herzog H, Witchley J, Noble SM, Leone VA, Chang EB. Pierre JF, et al. Among authors: leone va. Science. 2023 Aug 4;381(6657):502-508. doi: 10.1126/science.abq3178. Epub 2023 Aug 3. Science. 2023. PMID: 37535745 Free PMC article.
HMGB1 acts as an agent of host defense at the gut mucosal barrier.
Overstreet AC, Anderson B, Burge M, Zhu X, Tao Y, Cham CM, Michaud B, Horam S, Sangwan N, Dwidar M, Liu X, Santos A, Finney C, Dai Z, Leone VA, Messer JS. Overstreet AC, et al. Among authors: leone va. bioRxiv [Preprint]. 2023 May 30:2023.05.30.542477. doi: 10.1101/2023.05.30.542477. bioRxiv. 2023. PMID: 37398239 Free PMC article. Preprint.
Imbalanced gut microbiota predicts and drives the progression of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis in a fast-food diet mouse model.
Fei N, Miyoshi S, Hermanson JB, Miyoshi J, Xie B, DeLeon O, Hawkins M, Charlton W, D'Souza M, Hart J, Sulakhe D, Martinez-Guryn KB, Chang EB, Charlton MR, Leone VA. Fei N, et al. Among authors: leone va. bioRxiv [Preprint]. 2023 Jan 9:2023.01.09.523249. doi: 10.1101/2023.01.09.523249. bioRxiv. 2023. PMID: 36712061 Free PMC article. Preprint.
High-fat diet disrupts REG3γ and gut microbial rhythms promoting metabolic dysfunction.
Frazier K, Kambal A, Zale EA, Pierre JF, Hubert N, Miyoshi S, Miyoshi J, Ringus DL, Harris D, Yang K, Carroll K, Hermanson JB, Chlystek JS, Overmyer KA, Cham CM, Musch MW, Coon JJ, Chang EB, Leone VA. Frazier K, et al. Among authors: leone va. Cell Host Microbe. 2022 Jun 8;30(6):809-823.e6. doi: 10.1016/j.chom.2022.03.030. Epub 2022 Apr 18. Cell Host Microbe. 2022. PMID: 35439436 Free PMC article.
24 results