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Enhancer-instructed epigenetic landscape and chromatin compartmentalization dictate a primary antibody repertoire protective against specific bacterial pathogens.
Nat Immunol. 2023 Feb;24(2):320-336. doi: 10.1038/s41590-022-01402-z. Epub 2023 Jan 30.
Nat Immunol. 2023.
PMID: 36717722
Free PMC article.
Variable Extent of Lineage-Specificity and Developmental Stage-Specificity of Cohesin and CCCTC-Binding Factor Binding Within the Immunoglobulin and T Cell Receptor Loci.
Loguercio S, Barajas-Mora EM, Shih HY, Krangel MS, Feeney AJ.
Loguercio S, et al. Among authors: barajas mora em.
Front Immunol. 2018 Mar 8;9:425. doi: 10.3389/fimmu.2018.00425. eCollection 2018.
Front Immunol. 2018.
PMID: 29593713
Free PMC article.
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A B-Cell-Specific Enhancer Orchestrates Nuclear Architecture to Generate a Diverse Antigen Receptor Repertoire.
Barajas-Mora EM, Kleiman E, Xu J, Carrico NC, Lu H, Oltz EM, Murre C, Feeney AJ.
Barajas-Mora EM, et al.
Mol Cell. 2019 Jan 3;73(1):48-60.e5. doi: 10.1016/j.molcel.2018.10.013. Epub 2018 Nov 15.
Mol Cell. 2019.
PMID: 30449725
Free PMC article.
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Enhancers as regulators of antigen receptor loci three-dimensional chromatin structure.
Barajas-Mora EM, Feeney AJ.
Barajas-Mora EM, et al.
Transcription. 2020 Feb;11(1):37-51. doi: 10.1080/21541264.2019.1699383. Epub 2019 Dec 12.
Transcription. 2020.
PMID: 31829768
Free PMC article.
Review.
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Enhancers within the Ig V Gene Region Orchestrate Chromatin Topology and Regulate V Gene Rearrangement Frequency to Shape the B Cell Receptor Repertoire Specificities.
Barajas-Mora EM, Feeney AJ.
Barajas-Mora EM, et al.
J Immunol. 2023 Dec 1;211(11):1613-1622. doi: 10.4049/jimmunol.2300261.
J Immunol. 2023.
PMID: 37983521
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