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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Mitchell K, Sprowls SA, Arora S, Shakya S, Silver DJ, Goins CM, Wallace L, Roversi G, Schafer RE, Kay K, Miller TE, Lauko A, Bassett J, Kashyap A, D'Amato Kass J, Mulkearns-Hubert EE, Johnson S, Alvarado J, Rich JN, Holland EC, Paddison PJ, Patel AP, Stauffer SR, Hubert CG, Lathia JD. Mitchell K, et al. Among authors: sprowls sa. Genes Dev. 2023 Feb 1;37(3-4):86-102. doi: 10.1101/gad.349803.122. Epub 2023 Feb 2. Genes Dev. 2023. PMID: 36732025 Free PMC article.
GAP43-dependent mitochondria transfer from astrocytes enhances glioblastoma tumorigenicity.
Watson DC, Bayik D, Storevik S, Moreino SS, Sprowls SA, Han J, Augustsson MT, Lauko A, Sravya P, Røsland GV, Troike K, Tronstad KJ, Wang S, Sarnow K, Kay K, Lunavat TR, Silver DJ, Dayal S, Joseph JV, Mulkearns-Hubert E, Ystaas LAR, Deshpande G, Guyon J, Zhou Y, Magaut CR, Seder J, Neises L, Williford SE, Meiser J, Scott AJ, Sajjakulnukit P, Mears JA, Bjerkvig R, Chakraborty A, Daubon T, Cheng F, Lyssiotis CA, Wahl DR, Hjelmeland AB, Hossain JA, Miletic H, Lathia JD. Watson DC, et al. Among authors: sprowls sa. Nat Cancer. 2023 May;4(5):648-664. doi: 10.1038/s43018-023-00556-5. Epub 2023 May 11. Nat Cancer. 2023. PMID: 37169842 Free PMC article.
Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy.
Arsiwala TA, Blethen KE, Wolford CP, Panchal DM, Sprowls SA, Fladeland RA, Kielkowski BN, Pritt TA, Wang P, Wilson O, Carpenter JS, Finomore V, Rezai A, Lockman PR. Arsiwala TA, et al. Among authors: sprowls sa. Front Oncol. 2023 Feb 10;13:1104594. doi: 10.3389/fonc.2023.1104594. eCollection 2023. Front Oncol. 2023. PMID: 36845739 Free PMC article.
Characterization of passive permeability after low intensity focused ultrasound mediated blood-brain barrier disruption in a preclinical model.
Arsiwala TA, Sprowls SA, Blethen KE, Fladeland RA, Wolford CP, Kielkowski BN, Glass MJ, Wang P, Wilson O, Carpenter JS, Ranjan M, Finomore V, Rezai A, Lockman PR. Arsiwala TA, et al. Among authors: sprowls sa. Fluids Barriers CNS. 2022 Sep 8;19(1):72. doi: 10.1186/s12987-022-00369-1. Fluids Barriers CNS. 2022. PMID: 36076213 Free PMC article.
Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases.
Blethen KE, Arsiwala TA, Fladeland RA, Sprowls SA, Panchal DM, Adkins CE, Kielkowski BN, Earp LE, Glass MJ, Pritt TA, Cabuyao YM, Aulakh S, Lockman PR. Blethen KE, et al. Among authors: sprowls sa. Neurooncol Adv. 2021 Nov 27;3(Suppl 5):v133-v143. doi: 10.1093/noajnl/vdab123. eCollection 2021 Nov. Neurooncol Adv. 2021. PMID: 34859240 Free PMC article.
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