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Human PRPS1 filaments stabilize allosteric sites to regulate activity.
Hvorecny KL, Hargett K, Quispe JD, Kollman JM. Hvorecny KL, et al. Among authors: kollman jm. Nat Struct Mol Biol. 2023 Mar;30(3):391-402. doi: 10.1038/s41594-023-00921-z. Epub 2023 Feb 6. Nat Struct Mol Biol. 2023. PMID: 36747094 Free PMC article.
Human CTP synthase filament structure reveals the active enzyme conformation.
Lynch EM, Hicks DR, Shepherd M, Endrizzi JA, Maker A, Hansen JM, Barry RM, Gitai Z, Baldwin EP, Kollman JM. Lynch EM, et al. Among authors: kollman jm. Nat Struct Mol Biol. 2017 Jun;24(6):507-514. doi: 10.1038/nsmb.3407. Epub 2017 May 1. Nat Struct Mol Biol. 2017. PMID: 28459447 Free PMC article.
Lysogenic host-virus interactions in SAR11 marine bacteria.
Morris RM, Cain KR, Hvorecny KL, Kollman JM. Morris RM, et al. Among authors: kollman jm. Nat Microbiol. 2020 Aug;5(8):1011-1015. doi: 10.1038/s41564-020-0725-x. Epub 2020 May 18. Nat Microbiol. 2020. PMID: 32424337 Free PMC article.
BRCA1/BARD1 site-specific ubiquitylation of nucleosomal H2A is directed by BARD1.
Witus SR, Burrell AL, Farrell DP, Kang J, Wang M, Hansen JM, Pravat A, Tuttle LM, Stewart MD, Brzovic PS, Chatterjee C, Zhao W, DiMaio F, Kollman JM, Klevit RE. Witus SR, et al. Among authors: kollman jm. Nat Struct Mol Biol. 2021 Mar;28(3):268-277. doi: 10.1038/s41594-020-00556-4. Epub 2021 Feb 15. Nat Struct Mol Biol. 2021. PMID: 33589814 Free PMC article.
Structural basis for isoform-specific inhibition of human CTPS1.
Lynch EM, DiMattia MA, Albanese S, van Zundert GCP, Hansen JM, Quispe JD, Kennedy MA, Verras A, Borrelli K, Toms AV, Kaila N, Kreutter KD, McElwee JJ, Kollman JM. Lynch EM, et al. Among authors: kollman jm. Proc Natl Acad Sci U S A. 2021 Oct 5;118(40):e2107968118. doi: 10.1073/pnas.2107968118. Proc Natl Acad Sci U S A. 2021. PMID: 34583994 Free PMC article.
IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Burrell AL, Nie C, Said M, Simonet JC, Fernández-Justel D, Johnson MC, Quispe J, Buey RM, Peterson JR, Kollman JM. Burrell AL, et al. Among authors: kollman jm. Nat Struct Mol Biol. 2022 Jan;29(1):47-58. doi: 10.1038/s41594-021-00706-2. Epub 2022 Jan 10. Nat Struct Mol Biol. 2022. PMID: 35013599 Free PMC article.
Computational design of mechanically coupled axle-rotor protein assemblies.
Courbet A, Hansen J, Hsia Y, Bethel N, Park YJ, Xu C, Moyer A, Boyken SE, Ueda G, Nattermann U, Nagarajan D, Silva DA, Sheffler W, Quispe J, Nord A, King N, Bradley P, Veesler D, Kollman J, Baker D. Courbet A, et al. Science. 2022 Apr 22;376(6591):383-390. doi: 10.1126/science.abm1183. Epub 2022 Apr 21. Science. 2022. PMID: 35446645 Free PMC article.
69 results