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Late gene expression-deficient cytomegalovirus vectors elicit conventional T cells that do not protect against SIV.
JCI Insight. 2023 Mar 22;8(6):e164692. doi: 10.1172/jci.insight.164692.
JCI Insight. 2023.
PMID: 36749635
Free PMC article.
Modulation of MHC-E transport by viral decoy ligands is required for RhCMV/SIV vaccine efficacy.
Verweij MC, Hansen SG, Iyer R, John N, Malouli D, Morrow D, Scholz I, Womack J, Abdulhaqq S, Gilbride RM, Hughes CM, Ventura AB, Ford JC, Selseth AN, Oswald K, Shoemaker R, Berkemeier B, Bosche WJ, Hull M, Shao J, Sacha JB, Axthelm MK, Edlefsen PT, Lifson JD, Picker LJ, Früh K.
Verweij MC, et al.
Science. 2021 Apr 30;372(6541):eabe9233. doi: 10.1126/science.abe9233. Epub 2021 Mar 25.
Science. 2021.
PMID: 33766941
Free PMC article.
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CD8+ T cell targeting of tumor antigens presented by HLA-E.
Iyer RF, Verweij MC, Nair SS, Morrow D, Mansouri M, Chakravarty D, Beechwood T, Meyer C, Uebelhoer L, Lauron EJ, Selseth A, John N, Thin TH, Dzedzik S, Havenar-Daughton C, Axthelm MK, Douglas J, Korman A, Bhardwaj N, Tewari AK, Hansen S, Malouli D, Picker LJ, Früh K.
Iyer RF, et al.
Sci Adv. 2024 May 10;10(19):eadm7515. doi: 10.1126/sciadv.adm7515. Epub 2024 May 10.
Sci Adv. 2024.
PMID: 38728394
Free PMC article.
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The secreted protein Cowpox Virus 14 contributes to viral virulence and immune evasion by engaging Fc-gamma-receptors.
Iyer RF, Edwards DM, Kolb P, Raué HP, Nelson CA, Epperson ML, Slifka MK, Nolz JC, Hengel H, Fremont DH, Früh K.
Iyer RF, et al.
PLoS Pathog. 2022 Sep 19;18(9):e1010783. doi: 10.1371/journal.ppat.1010783. eCollection 2022 Sep.
PLoS Pathog. 2022.
PMID: 36121874
Free PMC article.
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