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Piperlongumine conjugates induce targeted protein degradation.
Pei J, Xiao Y, Liu X, Hu W, Sobh A, Yuan Y, Zhou S, Hua N, Mackintosh SG, Zhang X, Basso KB, Kamat M, Yang Q, Licht JD, Zheng G, Zhou D, Lv D. Pei J, et al. Among authors: xiao y. Cell Chem Biol. 2023 Feb 16;30(2):203-213.e17. doi: 10.1016/j.chembiol.2023.01.004. Epub 2023 Feb 6. Cell Chem Biol. 2023. PMID: 36750097 Free PMC article.
Discovery of histone deacetylase 3 (HDAC3)-specific PROTACs.
Xiao Y, Wang J, Zhao LY, Chen X, Zheng G, Zhang X, Liao D. Xiao Y, et al. Chem Commun (Camb). 2020 Aug 25;56(68):9866-9869. doi: 10.1039/d0cc03243c. Chem Commun (Camb). 2020. PMID: 32840532 Free PMC article.
Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy.
Wang L, Xiao Y, Luo Y, Master RP, Mo J, Kim MC, Liu Y, Patel UM, Li X, Shaffer D, Guertin KR, Moser E, Smalley KS, Zhou D, Zheng G, Zhang W. Wang L, et al. Among authors: xiao y. bioRxiv [Preprint]. 2023 Aug 13:2023.08.09.552650. doi: 10.1101/2023.08.09.552650. bioRxiv. 2023. PMID: 37609171 Free PMC article. Updated. Preprint.
PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy.
Wang L, Xiao Y, Luo Y, Master RP, Mo J, Kim MC, Liu Y, Maharjan CK, Patel UM, De U, Carelock ME, Tithi TI, Li X, Shaffer DR, Guertin KR, Zhuang H, Moser E, Smalley KSM, Lv D, Zhou D, Zheng G, Zhang W. Wang L, et al. Among authors: xiao y. J Exp Med. 2024 Mar 4;221(3):e20231519. doi: 10.1084/jem.20231519. Epub 2024 Feb 9. J Exp Med. 2024. PMID: 38334978 Free PMC article.
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