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Page 1
Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.
Mensah MA, Niskanen H, Magalhaes AP, Basu S, Kircher M, Sczakiel HL, Reiter AMV, Elsner J, Meinecke P, Biskup S, Chung BHY, Dombrowsky G, Eckmann-Scholz C, Hitz MP, Hoischen A, Holterhus PM, Hülsemann W, Kahrizi K, Kalscheuer VM, Kan A, Krumbiegel M, Kurth I, Leubner J, Longardt AC, Moritz JD, Najmabadi H, Skipalova K, Snijders Blok L, Tzschach A, Wiedersberg E, Zenker M, Garcia-Cabau C, Buschow R, Salvatella X, Kraushar ML, Mundlos S, Caliebe A, Spielmann M, Horn D, Hnisz D. Mensah MA, et al. Among authors: niskanen h. Nature. 2023 Feb;614(7948):564-571. doi: 10.1038/s41586-022-05682-1. Epub 2023 Feb 8. Nature. 2023. PMID: 36755093 Free PMC article.
Translatome profiling reveals Itih4 as a novel smooth muscle cell-specific gene in atherosclerosis.
Ravindran A, Holappa L, Niskanen H, Skovorodkin I, Kaisto S, Beter M, Kiema M, Selvarajan I, Nurminen V, Aavik E, Aherrahrou R, Pasonen-Seppänen S, Fortino V, Laakkonen JP, Ylä-Herttuala S, Vainio S, Örd T, Kaikkonen MU. Ravindran A, et al. Among authors: niskanen h. Cardiovasc Res. 2024 Jan 30:cvae028. doi: 10.1093/cvr/cvae028. Online ahead of print. Cardiovasc Res. 2024. PMID: 38289873
Progression of herpesvirus infection remodels mitochondrial organization and metabolism.
Leclerc S, Gupta A, Ruokolainen V, Chen JH, Kunnas K, Ekman AA, Niskanen H, Belevich I, Vihinen H, Turkki P, Perez-Berna AJ, Kapishnikov S, Mäntylä E, Harkiolaki M, Dufour E, Hytönen V, Pereiro E, McEnroe T, Fahy K, Kaikkonen MU, Jokitalo E, Larabell CA, Weinhardt V, Mattola S, Aho V, Vihinen-Ranta M. Leclerc S, et al. Among authors: niskanen h. PLoS Pathog. 2024 Apr 15;20(4):e1011829. doi: 10.1371/journal.ppat.1011829. eCollection 2024 Apr. PLoS Pathog. 2024. PMID: 38620036 Free PMC article.
Hypoxic regulation of hypoxia inducible factor 1 alpha via antisense transcription.
Downes N, Niskanen H, Tomas Bosch V, Taipale M, Godiwala M, Väänänen MA, Turunen TA, Aavik E, Laham-Karam N, Ylä-Herttuala S, Kaikkonen MU. Downes N, et al. Among authors: niskanen h. J Biol Chem. 2023 Nov;299(11):105291. doi: 10.1016/j.jbc.2023.105291. Epub 2023 Sep 23. J Biol Chem. 2023. PMID: 37748649 Free PMC article.
Dissecting the polygenic basis of atherosclerosis via disease-associated cell state signatures.
Örd T, Lönnberg T, Nurminen V, Ravindran A, Niskanen H, Kiema M, Õunap K, Maria M, Moreau PR, Mishra PP, Palani S, Virta J, Liljenbäck H, Aavik E, Roivainen A, Ylä-Herttuala S, Laakkonen JP, Lehtimäki T, Kaikkonen MU. Örd T, et al. Among authors: niskanen h. Am J Hum Genet. 2023 May 4;110(5):722-740. doi: 10.1016/j.ajhg.2023.03.013. Epub 2023 Apr 14. Am J Hum Genet. 2023. PMID: 37060905 Free PMC article.
Hijacking of transcriptional condensates by endogenous retroviruses.
Asimi V, Sampath Kumar A, Niskanen H, Riemenschneider C, Hetzel S, Naderi J, Fasching N, Popitsch N, Du M, Kretzmer H, Smith ZD, Weigert R, Walther M, Mamde S, Meierhofer D, Wittler L, Buschow R, Timmermann B, Cisse II, Ameres SL, Meissner A, Hnisz D. Asimi V, et al. Among authors: niskanen h. Nat Genet. 2022 Aug;54(8):1238-1247. doi: 10.1038/s41588-022-01132-w. Epub 2022 Jul 21. Nat Genet. 2022. PMID: 35864192 Free PMC article.
Polycomb Repressive Complex 2 Regulates Genes Necessary for Intestinal Microfold Cell (M Cell) Development.
George JJ, Oittinen M, Martin-Diaz L, Zapilko V, Iqbal S, Rintakangas T, Arrojo Martins FT, Niskanen H, Katajisto P, Kaikkonen MU, Viiri K. George JJ, et al. Among authors: niskanen h. Cell Mol Gastroenterol Hepatol. 2021;12(3):873-889. doi: 10.1016/j.jcmgh.2021.05.014. Epub 2021 May 28. Cell Mol Gastroenterol Hepatol. 2021. PMID: 34058415 Free PMC article.
The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages.
Huang Z, Liang N, Goñi S, Damdimopoulos A, Wang C, Ballaire R, Jager J, Niskanen H, Han H, Jakobsson T, Bracken AP, Aouadi M, Venteclef N, Kaikkonen MU, Fan R, Treuter E. Huang Z, et al. Among authors: niskanen h. Mol Cell. 2021 Mar 4;81(5):953-968.e9. doi: 10.1016/j.molcel.2020.12.040. Epub 2021 Jan 26. Mol Cell. 2021. PMID: 33503407 Free article.
33 results