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Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.
Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, Loomis C, Heguy A, Sherman MH, Lund AW, Welling TH, Dolgalev I, Tsirigos A, Simeone DM. Werba G, et al. Among authors: heguy a. Nat Commun. 2023 Feb 13;14(1):797. doi: 10.1038/s41467-023-36296-4. Nat Commun. 2023. PMID: 36781852 Free PMC article.
The integrated landscape of driver genomic alterations in glioblastoma.
Frattini V, Trifonov V, Chan JM, Castano A, Lia M, Abate F, Keir ST, Ji AX, Zoppoli P, Niola F, Danussi C, Dolgalev I, Porrati P, Pellegatta S, Heguy A, Gupta G, Pisapia DJ, Canoll P, Bruce JN, McLendon RE, Yan H, Aldape K, Finocchiaro G, Mikkelsen T, Privé GG, Bigner DD, Lasorella A, Rabadan R, Iavarone A. Frattini V, et al. Among authors: heguy a. Nat Genet. 2013 Oct;45(10):1141-9. doi: 10.1038/ng.2734. Epub 2013 Aug 5. Nat Genet. 2013. PMID: 23917401 Free PMC article.
Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.
Cerrone M, Montnach J, Lin X, Zhao YT, Zhang M, Agullo-Pascual E, Leo-Macias A, Alvarado FJ, Dolgalev I, Karathanos TV, Malkani K, Van Opbergen CJM, van Bavel JJA, Yang HQ, Vasquez C, Tester D, Fowler S, Liang F, Rothenberg E, Heguy A, Morley GE, Coetzee WA, Trayanova NA, Ackerman MJ, van Veen TAB, Valdivia HH, Delmar M. Cerrone M, et al. Among authors: heguy a. Nat Commun. 2017 Jul 24;8(1):106. doi: 10.1038/s41467-017-00127-0. Nat Commun. 2017. PMID: 28740174 Free PMC article.
Bacteriophages as potential new mammalian pathogens.
Tetz GV, Ruggles KV, Zhou H, Heguy A, Tsirigos A, Tetz V. Tetz GV, et al. Among authors: heguy a. Sci Rep. 2017 Aug 1;7(1):7043. doi: 10.1038/s41598-017-07278-6. Sci Rep. 2017. PMID: 28765534 Free PMC article.
Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.
Romero R, Sayin VI, Davidson SM, Bauer MR, Singh SX, LeBoeuf SE, Karakousi TR, Ellis DC, Bhutkar A, Sánchez-Rivera FJ, Subbaraj L, Martinez B, Bronson RT, Prigge JR, Schmidt EE, Thomas CJ, Goparaju C, Davies A, Dolgalev I, Heguy A, Allaj V, Poirier JT, Moreira AL, Rudin CM, Pass HI, Vander Heiden MG, Jacks T, Papagiannakopoulos T. Romero R, et al. Among authors: heguy a. Nat Med. 2017 Nov;23(11):1362-1368. doi: 10.1038/nm.4407. Epub 2017 Oct 2. Nat Med. 2017. PMID: 28967920 Free PMC article.
Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells.
Bayin NS, Frenster JD, Sen R, Si S, Modrek AS, Galifianakis N, Dolgalev I, Ortenzi V, Illa-Bochaca I, Khahera A, Serrano J, Chiriboga L, Zagzag D, Golfinos JG, Doyle W, Tsirigos A, Heguy A, Chesler M, Barcellos-Hoff MH, Snuderl M, Placantonakis DG. Bayin NS, et al. Among authors: heguy a. Oncotarget. 2017 May 23;8(39):64932-64953. doi: 10.18632/oncotarget.18117. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029402 Free PMC article.
206 results