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Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.
Werba G, Weissinger D, Kawaler EA, Zhao E, Kalfakakou D, Dhara S, Wang L, Lim HB, Oh G, Jing X, Beri N, Khanna L, Gonda T, Oberstein P, Hajdu C, Loomis C, Heguy A, Sherman MH, Lund AW, Welling TH, Dolgalev I, Tsirigos A, Simeone DM. Werba G, et al. Among authors: simeone dm. Nat Commun. 2023 Feb 13;14(1):797. doi: 10.1038/s41467-023-36296-4. Nat Commun. 2023. PMID: 36781852 Free PMC article.
FOXP3 defines regulatory T cells in human tumor and autoimmune disease.
Kryczek I, Liu R, Wang G, Wu K, Shu X, Szeliga W, Vatan L, Finlayson E, Huang E, Simeone D, Redman B, Welling TH, Chang A, Zou W. Kryczek I, et al. Cancer Res. 2009 May 1;69(9):3995-4000. doi: 10.1158/0008-5472.CAN-08-3804. Epub 2009 Apr 21. Cancer Res. 2009. PMID: 19383912 Free article.
c-Met is a marker of pancreatic cancer stem cells and therapeutic target.
Li C, Wu JJ, Hynes M, Dosch J, Sarkar B, Welling TH, Pasca di Magliano M, Simeone DM. Li C, et al. Among authors: simeone dm. Gastroenterology. 2011 Dec;141(6):2218-2227.e5. doi: 10.1053/j.gastro.2011.08.009. Epub 2011 Aug 22. Gastroenterology. 2011. PMID: 21864475
GM-CSF Mediates Mesenchymal-Epithelial Cross-talk in Pancreatic Cancer.
Waghray M, Yalamanchili M, Dziubinski M, Zeinali M, Erkkinen M, Yang H, Schradle KA, Urs S, Pasca Di Magliano M, Welling TH, Palmbos PL, Abel EV, Sahai V, Nagrath S, Wang L, Simeone DM. Waghray M, et al. Among authors: simeone dm. Cancer Discov. 2016 Aug;6(8):886-99. doi: 10.1158/2159-8290.CD-15-0947. Epub 2016 May 16. Cancer Discov. 2016. PMID: 27184426 Free PMC article.
HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties.
Abel EV, Goto M, Magnuson B, Abraham S, Ramanathan N, Hotaling E, Alaniz AA, Kumar-Sinha C, Dziubinski ML, Urs S, Wang L, Shi J, Waghray M, Ljungman M, Crawford HC, Simeone DM. Abel EV, et al. Among authors: simeone dm. Elife. 2018 Aug 3;7:e33947. doi: 10.7554/eLife.33947. Elife. 2018. PMID: 30074477 Free PMC article.
ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis.
Wang L, Yang H, Zamperone A, Diolaiti D, Palmbos PL, Abel EV, Purohit V, Dolgalev I, Rhim AD, Ljungman M, Hadju CH, Halbrook CJ, Bar-Sagi D, di Magliano MP, Crawford HC, Simeone DM. Wang L, et al. Among authors: simeone dm. Genes Dev. 2019 Jun 1;33(11-12):641-655. doi: 10.1101/gad.323303.118. Epub 2019 May 2. Genes Dev. 2019. PMID: 31048544 Free PMC article.
New Labyrinth Microfluidic Device Detects Circulating Tumor Cells Expressing Cancer Stem Cell Marker and Circulating Tumor Microemboli in Hepatocellular Carcinoma.
Wan S, Kim TH, Smith KJ, Delaney R, Park GS, Guo H, Lin E, Plegue T, Kuo N, Steffes J, Leu C, Simeone DM, Razimulava N, Parikh ND, Nagrath S, Welling TH. Wan S, et al. Among authors: simeone dm. Sci Rep. 2019 Dec 9;9(1):18575. doi: 10.1038/s41598-019-54960-y. Sci Rep. 2019. PMID: 31819089 Free PMC article.
219 results