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SGN-CD228A Is an Investigational CD228-Directed Antibody-Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models.
Mol Cancer Ther. 2023 Apr 3;22(4):421-434. doi: 10.1158/1535-7163.MCT-22-0401.
Mol Cancer Ther. 2023.
PMID: 36800443
Free PMC article.
Clinical Trial.
Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates.
Burke PJ, Hamilton JZ, Pires TA, Setter JR, Hunter JH, Cochran JH, Waight AB, Gordon KA, Toki BE, Emmerton KK, Zeng W, Stone IJ, Senter PD, Lyon RP, Jeffrey SC.
Burke PJ, et al. Among authors: pires ta.
Mol Cancer Ther. 2016 May;15(5):938-45. doi: 10.1158/1535-7163.MCT-16-0038. Epub 2016 Mar 4.
Mol Cancer Ther. 2016.
PMID: 26944920
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Glucuronide-Linked Antibody-Tubulysin Conjugates Display Activity in MDR+ and Heterogeneous Tumor Models.
Burke PJ, Hamilton JZ, Pires TA, Lai HWH, Leiske CI, Emmerton KK, Waight AB, Senter PD, Lyon RP, Jeffrey SC.
Burke PJ, et al. Among authors: pires ta.
Mol Cancer Ther. 2018 Aug;17(8):1752-1760. doi: 10.1158/1535-7163.MCT-18-0073. Epub 2018 Jun 4.
Mol Cancer Ther. 2018.
PMID: 29866744
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Improving Antibody-Tubulysin Conjugates through Linker Chemistry and Site-Specific Conjugation.
Hamilton JZ, Pires TA, Mitchell JA, Cochran JH, Emmerton KK, Zaval M, Stone IJ, Anderson ME, Jin S, Waight AB, Lyon RP, Senter PD, Jeffrey SC, Burke PJ.
Hamilton JZ, et al. Among authors: pires ta.
ChemMedChem. 2021 Apr 8;16(7):1077-1081. doi: 10.1002/cmdc.202000889. Epub 2021 Feb 12.
ChemMedChem. 2021.
PMID: 33369163
Free PMC article.
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Effects of Cationic Proteins on Gold Nanoparticle/Aptamer Assays.
Pires TA, Narovec CM, Whelan RJ.
Pires TA, et al.
ACS Omega. 2017 Nov 30;2(11):8222-8226. doi: 10.1021/acsomega.7b01336. Epub 2017 Nov 20.
ACS Omega. 2017.
PMID: 29214237
Free PMC article.
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