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PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy.
Zhang D, Li AM, Hu G, Huang M, Yang F, Zhang L, Wellen KE, Xu X, Conn CS, Zou W, Kahn M, Rhoades SD, Weljie AM, Fuchs SY, Amankulor N, Yoshor D, Ye J, Koumenis C, Gong Y, Fan Y. Zhang D, et al. Among authors: amankulor n. Cell Metab. 2023 Mar 7;35(3):517-534.e8. doi: 10.1016/j.cmet.2023.01.010. Epub 2023 Feb 17. Cell Metab. 2023. PMID: 36804058 Free PMC article.
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Casillo SM, Gatesman TA, Chilukuri A, Varadharajan S, Johnson BJ, David Premkumar DR, Jane EP, Plute TJ, Koncar RF, Stanton AJ, Biagi-Junior CAO, Barber CS, Halbert ME, Golbourn BJ, Halligan K, Cruz AF, Mansi NM, Cheney A, Mullett SJ, Land CV, Perez JL, Myers MI, Agrawal N, Michel JJ, Chang YF, Vaske OM, MichaelRaj A, Lieberman FS, Felker J, Shiva S, Bertrand KC, Amankulor N, Hadjipanayis CG, Abdullah KG, Zinn PO, Friedlander RM, Abel TJ, Nazarian J, Venneti S, Filbin MG, Gelhaus SL, Mack SC, Pollack IF, Agnihotri S. Casillo SM, et al. Among authors: amankulor n. Cell Rep. 2024 Jan 23;43(1):113557. doi: 10.1016/j.celrep.2023.113557. Epub 2023 Dec 18. Cell Rep. 2024. PMID: 38113141 Free article.
TP53-PTEN-NF1 depletion in human brain organoids produces a glioma phenotype in vitro.
Singh SK, Wang Y, Habib A, Priyadarshini M, Kodavali CV, Chen A, Ma W, Wang J, Hameed NUF, Hu B, Fuller GN, Kulich SM, Amankulor N, Colen RR, Edwards LA, Zinn PO. Singh SK, et al. Among authors: amankulor n. Front Oncol. 2023 Oct 10;13:1279806. doi: 10.3389/fonc.2023.1279806. eCollection 2023. Front Oncol. 2023. PMID: 37881491 Free PMC article.
A novel ARIH1::BRAF fusion in a glioma.
Xu E, Stone SL, Zhong Y, Golenberg N, Qiu L, Abdullaev Z, Aldape K, Bagley L, Halpern CH, Amankulor N, Nasrallah MP. Xu E, et al. Among authors: amankulor n. J Neuropathol Exp Neurol. 2023 Oct 20;82(11):966-969. doi: 10.1093/jnen/nlad074. J Neuropathol Exp Neurol. 2023. PMID: 37742132 Free PMC article. No abstract available.
BRAF V600E in a preclinical model of pleomorphic Xanthoastrocytoma: Analysis of the tumor microenvironment and immune cell infiltration dynamics in vivo.
Canella A, Nazzaro M, Artomov M, Rao Venkata LP, Thomas D, Lyberger J, Ukhatov A, Xing YL, Miller K, Behbehani G, Amankulor NM, Petritsch CK, Rajappa P. Canella A, et al. Among authors: amankulor nm. Mol Ther Oncol. 2024 Apr 25;32(2):200808. doi: 10.1016/j.omton.2024.200808. eCollection 2024 Jun 20. Mol Ther Oncol. 2024. PMID: 38784952 Free PMC article.
Distinguishing Progression from Pseudoprogression in Glioblastoma Using 18F-Fluciclovine PET.
Nabavizadeh A, Bagley SJ, Doot RK, Ware JB, Young AJ, Ghodasara S, Zhao C, Anderson H, Schubert E, Carpenter EL, Till J, Henderson F Jr, Pantel AR, Chen HI, Lee JYK, Amankulor NM, O'Rourke DM, Desai A, Nasrallah MP, Brem S. Nabavizadeh A, et al. J Nucl Med. 2023 Jun;64(6):852-858. doi: 10.2967/jnumed.122.264812. Epub 2022 Dec 22. J Nucl Med. 2023. PMID: 36549916 Free article.
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas.
Youngblood MW, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo JD, Miyagishima DF, Barak T, Nishimura S, Harmancı AS, Clark VE, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir MN, Özduman K, Kilic T, Knight JR, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger AB, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Youngblood MW, et al. Among authors: amankulor n. Nat Commun. 2023 Oct 7;14(1):6279. doi: 10.1038/s41467-023-41926-y. Nat Commun. 2023. PMID: 37805627 Free PMC article.
Preoperative stereotactic radiosurgery for cerebral metastases: safe, effective, and decreases steroid dependency.
Mallela AN, Iheagwara UK, Fogg D, Anthony A, Gersey ZC, Zhang X, Abou-Al-Shaar H, Anand SK, Xu E, Zinn PO, Burton S, Quinn A, Ozhasoglu C, Clump DA, Siddiqui Z, Amankulor NM. Mallela AN, et al. Among authors: amankulor nm. J Neurosurg. 2024 May 10:1-11. doi: 10.3171/2024.2.JNS232426. Online ahead of print. J Neurosurg. 2024. PMID: 38728761
81 results