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PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy.
Zhang D, Li AM, Hu G, Huang M, Yang F, Zhang L, Wellen KE, Xu X, Conn CS, Zou W, Kahn M, Rhoades SD, Weljie AM, Fuchs SY, Amankulor N, Yoshor D, Ye J, Koumenis C, Gong Y, Fan Y. Zhang D, et al. Among authors: ye j. Cell Metab. 2023 Mar 7;35(3):517-534.e8. doi: 10.1016/j.cmet.2023.01.010. Epub 2023 Feb 17. Cell Metab. 2023. PMID: 36804058 Free PMC article.
Hypoxia and the unfolded protein response.
Koumenis C, Bi M, Ye J, Feldman D, Koong AC. Koumenis C, et al. Among authors: ye j. Methods Enzymol. 2007;435:275-93. doi: 10.1016/S0076-6879(07)35014-3. Methods Enzymol. 2007. PMID: 17998059
Modulation of CCAAT/enhancer binding protein homologous protein (CHOP)-dependent DR5 expression by nelfinavir sensitizes glioblastoma multiforme cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).
Tian X, Ye J, Alonso-Basanta M, Hahn SM, Koumenis C, Dorsey JF. Tian X, et al. Among authors: ye j. J Biol Chem. 2011 Aug 19;286(33):29408-29416. doi: 10.1074/jbc.M110.197665. Epub 2011 Jun 22. J Biol Chem. 2011. PMID: 21697087 Free PMC article.
ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.
Tameire F, Verginadis II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C. Tameire F, et al. Among authors: ye j. Nat Cell Biol. 2019 Jul;21(7):889-899. doi: 10.1038/s41556-019-0347-9. Epub 2019 Jul 1. Nat Cell Biol. 2019. PMID: 31263264 Free PMC article.
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