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Page 1
Population pharmacokinetic modelling to characterize the effect of chronic kidney disease on tenofovir exposure after tenofovir alafenamide administration.
Thoueille P, Alves Saldanha S, Desfontaine V, Kusejko K, Courlet P, Andre P, Cavassini M, Decosterd LA, Buclin T, Guidi M; Swiss HIV Cohort Study. Thoueille P, et al. Among authors: desfontaine v. J Antimicrob Chemother. 2023 Jun 1;78(6):1433-1443. doi: 10.1093/jac/dkad103. J Antimicrob Chemother. 2023. PMID: 37042359 Free PMC article.
Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies.
Biniecka P, Matsumoto S, Belotti A, Joussot J, Bai JF, Majjigapu SR, Thoueille P, Spaggiari D, Desfontaine V, Piacente F, Bruzzone S, Cea M, Decosterd LA, Vogel P, Nencioni A, Duchosal MA, Nahimana A. Biniecka P, et al. Among authors: desfontaine v. Molecules. 2023 Feb 16;28(4):1897. doi: 10.3390/molecules28041897. Molecules. 2023. PMID: 36838885 Free PMC article.
Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine.
Desfontaine V, Guinchard S, Marques S, Vocat A, Moulfi F, Versace F, Huser-Pitteloud J, Ivanyuk A, Bardinet C, Makarov V, Ryabova O, André P, Prod'Hom S, Chtioui H, Buclin T, Cole ST, Decosterd L. Desfontaine V, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jan 15;1215:123555. doi: 10.1016/j.jchromb.2022.123555. Epub 2022 Dec 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 36563654 Free PMC article.
Development and validation of a liquid chromatography coupled to tandem mass spectrometry method for the monitoring of temsavir plasma concentrations in people living with HIV.
Thoueille P, Seybold U, Decosterd LA, Desfontaine V. Thoueille P, et al. Among authors: desfontaine v. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jan 1;1214:123575. doi: 10.1016/j.jchromb.2022.123575. Epub 2022 Dec 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 36542988 Free article.
A battery of tandem mass spectrometry assays with stable isotope-dilution for the quantification of 15 anti-tuberculosis drugs and two metabolites in patients with susceptible-, multidrug-resistant- and extensively drug-resistant tuberculosis.
Mercier T, Desfontaine V, Cruchon S, Da Silva Pereira Clara JA, Briki M, Mazza-Stalder J, Kajkus A, Burger R, Suttels V, Buclin T, Opota O, Koehler N, Sanchez Carballo PM, Lange C, André P, Decosterd LA, Choong E. Mercier T, et al. Among authors: desfontaine v. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Nov 15;1211:123456. doi: 10.1016/j.jchromb.2022.123456. Epub 2022 Sep 20. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 36240540
Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.
Courlet P, Alves Saldanha S, Cavassini M, Marzolini C, Choong E, Csajka C, Günthard HF, André P, Buclin T, Desfontaine V, Decosterd LA. Courlet P, et al. Among authors: desfontaine v. J Mass Spectrom. 2020 Jun;55(6):e4506. doi: 10.1002/jms.4506. Epub 2020 Mar 11. J Mass Spectrom. 2020. PMID: 32160389 Free PMC article.
UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV.
Courlet P, Spaggiari D, Desfontaine V, Cavassini M, Alves Saldanha S, Buclin T, Marzolini C, Csajka C, Decosterd LA. Courlet P, et al. Among authors: desfontaine v. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Sep 1;1125:121733. doi: 10.1016/j.jchromb.2019.121733. Epub 2019 Jul 25. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 31374423
Development and validation of a multiplex UHPLC-MS/MS method for the determination of the investigational antibiotic against multi-resistant tuberculosis macozinone (PBTZ169) and five active metabolites in human plasma.
Spaggiari D, Desfontaine V, Cruchon S, Guinchard S, Vocat A, Blattes E, Pitteloud J, Ciullini L, Bardinet C, Ivanyuk A, Makarov V, Ryabova O, Buclin T, Cole ST, Decosterd LA. Spaggiari D, et al. Among authors: desfontaine v. PLoS One. 2019 May 31;14(5):e0217139. doi: 10.1371/journal.pone.0217139. eCollection 2019. PLoS One. 2019. PMID: 31150423 Free PMC article.
First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities.
Dispas A, Marini R, Desfontaine V, Veuthey JL, Kotoni D, Losacco LG, Clarke A, Muscat Galea C, Mangelings D, Jocher BM, Regalado EL, Plachká K, Nováková L, Wuyts B, François I, Gray M, Aubin AJ, Tarafder A, Cazes M, Desvignes C, Villemet L, Sarrut M, Raimbault A, Lemasson E, Lesellier E, West C, Leek T, Wong M, Dai L, Zhang K, Grand-Guillaume Perrenoud A, Brunelli C, Hennig P, Bertin S, Mauge F, Da Costa N, Farrell WP, Hill M, Desphande N, Grangrade M, Sadaphule S, Yadav R, Rane S, Shringare S, Iguiniz M, Heinisch S, Lefevre J, Corbel E, Roques N, Heyden YV, Guillarme D, Hubert P. Dispas A, et al. Among authors: desfontaine v. J Pharm Biomed Anal. 2018 Nov 30;161:414-424. doi: 10.1016/j.jpba.2018.08.042. Epub 2018 Aug 23. J Pharm Biomed Anal. 2018. PMID: 30216790
Applicability of supercritical fluid chromatography - mass spectrometry to metabolomics. I - Optimization of separation conditions for the simultaneous analysis of hydrophilic and lipophilic substances.
Desfontaine V, Losacco GL, Gagnebin Y, Pezzatti J, Farrell WP, González-Ruiz V, Rudaz S, Veuthey JL, Guillarme D. Desfontaine V, et al. J Chromatogr A. 2018 Aug 10;1562:96-107. doi: 10.1016/j.chroma.2018.05.055. Epub 2018 May 28. J Chromatogr A. 2018. PMID: 29861304
22 results