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Identification of SARS-CoV-2 Mpro inhibitors containing P1' 4-fluorobenzothiazole moiety highly active against SARS-CoV-2.
Higashi-Kuwata N, Tsuji K, Hayashi H, Bulut H, Kiso M, Imai M, Ogata-Aoki H, Ishii T, Kobayakawa T, Nakano K, Takamune N, Kishimoto N, Hattori SI, Das D, Uemura Y, Shimizu Y, Aoki M, Hasegawa K, Suzuki S, Nishiyama A, Saruwatari J, Shimizu Y, Sukenaga Y, Takamatsu Y, Tsuchiya K, Maeda K, Yoshimura K, Iida S, Ozono S, Suzuki T, Okamura T, Misumi S, Kawaoka Y, Tamamura H, Mitsuya H. Higashi-Kuwata N, et al. Among authors: tsuchiya k. Nat Commun. 2023 Feb 25;14(1):1076. doi: 10.1038/s41467-023-36729-0. Nat Commun. 2023. PMID: 36841831 Free PMC article.
Involvement of the second extracellular loop and transmembrane residues of CCR5 in inhibitor binding and HIV-1 fusion: insights into the mechanism of allosteric inhibition.
Maeda K, Das D, Yin PD, Tsuchiya K, Ogata-Aoki H, Nakata H, Norman RB, Hackney LA, Takaoka Y, Mitsuya H. Maeda K, et al. Among authors: tsuchiya k. J Mol Biol. 2008 Sep 12;381(4):956-74. doi: 10.1016/j.jmb.2008.06.041. Epub 2008 Jun 20. J Mol Biol. 2008. PMID: 18590744 Free PMC article.
Neutralization of SARS-CoV-2 with IgG from COVID-19-convalescent plasma.
Maeda K, Higashi-Kuwata N, Kinoshita N, Kutsuna S, Tsuchiya K, Hattori SI, Matsuda K, Takamatsu Y, Gatanaga H, Oka S, Sugiyama H, Ohmagari N, Mitsuya H. Maeda K, et al. Among authors: tsuchiya k. Sci Rep. 2021 Mar 10;11(1):5563. doi: 10.1038/s41598-021-84733-5. Sci Rep. 2021. PMID: 33692457 Free PMC article.
A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators.
Matsuda K, Kobayakawa T, Kariya R, Tsuchiya K, Ryu S, Tsuji K, Ishii T, Gatanaga H, Yoshimura K, Okada S, Hamada A, Mitsuya H, Tamamura H, Maeda K. Matsuda K, et al. Among authors: tsuchiya k. Front Microbiol. 2021 Mar 17;12:636276. doi: 10.3389/fmicb.2021.636276. eCollection 2021. Front Microbiol. 2021. PMID: 33815322 Free PMC article.
Asymptomatic COVID-19 re-infection in a Japanese male by elevated half-maximal inhibitory concentration (IC50) of neutralizing antibodies.
Inada M, Ishikane M, Terada M, Matsunaga A, Maeda K, Tsuchiya K, Miura K, Sairenji Y, Kinoshita N, Ujiie M, Kutsuna S, Ishizaka Y, Mitsuya H, Ohmagari N. Inada M, et al. Among authors: tsuchiya k. J Infect Chemother. 2021 Jul;27(7):1063-1067. doi: 10.1016/j.jiac.2021.04.017. Epub 2021 Apr 24. J Infect Chemother. 2021. PMID: 33962861 Free PMC article.
N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism.
Hayashi Y, Tsuchiya K, Yamamoto M, Nemoto-Sasaki Y, Tanigawa K, Hama K, Ueda Y, Tanikawa T, Gohda J, Maeda K, Inoue JI, Yamashita A. Hayashi Y, et al. Among authors: tsuchiya k. J Virol. 2021 Aug 10;95(17):e0080721. doi: 10.1128/JVI.00807-21. Epub 2021 Aug 10. J Virol. 2021. PMID: 34106748 Free PMC article.
Correlates of neutralizing/SARS-CoV-2-S1-binding antibody response with adverse effects and immune kinetics in BNT162b2-vaccinated individuals.
Maeda K, Amano M, Uemura Y, Tsuchiya K, Matsushima T, Noda K, Shimizu Y, Fujiwara A, Takamatsu Y, Ichikawa Y, Nishimura H, Kinoshita M, Matsumoto S, Gatanaga H, Yoshimura K, Oka SI, Mikami A, Sugiura W, Sato T, Yoshida T, Shimada S, Mitsuya H. Maeda K, et al. Among authors: tsuchiya k. Sci Rep. 2021 Nov 24;11(1):22848. doi: 10.1038/s41598-021-01930-y. Sci Rep. 2021. PMID: 34819514 Free PMC article.
A widely distributed HIV-1 provirus elimination assay to evaluate latency-reversing agents in vitro.
Matsuda K, Islam S, Takada T, Tsuchiya K, Yang Tan BJ, Hattori SI, Katsuya H, Kitagawa K, Kim KS, Matsuo M, Sugata K, Delino NS, Gatanaga H, Yoshimura K, Matsushita S, Mitsuya H, Iwami S, Satou Y, Maeda K. Matsuda K, et al. Among authors: tsuchiya k. Cell Rep Methods. 2021 Nov 29;1(8):100122. doi: 10.1016/j.crmeth.2021.100122. eCollection 2021 Dec 20. Cell Rep Methods. 2021. PMID: 35475215 Free PMC article.
2,978 results