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Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects.
Jain S, Rick JW, Joshi RS, Beniwal A, Spatz J, Gill S, Chang AC, Choudhary N, Nguyen AT, Sudhir S, Chalif EJ, Chen JS, Chandra A, Haddad AF, Wadhwa H, Shah SS, Choi S, Hayes JL, Wang L, Yagnik G, Costello JF, Diaz A, Heiland DH, Aghi MK. Jain S, et al. Among authors: costello jf. J Clin Invest. 2023 Mar 1;133(5):e147087. doi: 10.1172/JCI147087. J Clin Invest. 2023. PMID: 36856115 Free PMC article.
"De novo replication repair deficient glioblastoma, IDH-wildtype" is a distinct glioblastoma subtype in adults that may benefit from immune checkpoint blockade.
Hadad S, Gupta R, Oberheim Bush NA, Taylor JW, Villanueva-Meyer JE, Young JS, Wu J, Ravindranathan A, Zhang Y, Warrier G, McCoy L, Shai A, Pekmezci M, Perry A, Bollen AW, Phillips JJ, Braunstein SE, Raleigh DR, Theodosopoulos P, Aghi MK, Chang EF, Hervey-Jumper SL, Costello JF, de Groot J, Butowski NA, Clarke JL, Chang SM, Berger MS, Molinaro AM, Solomon DA. Hadad S, et al. Among authors: costello jf. Acta Neuropathol. 2023 Dec 11;147(1):3. doi: 10.1007/s00401-023-02654-1. Acta Neuropathol. 2023. PMID: 38079020 Free PMC article.
Epigenetic mechanisms in glioblastoma multiforme.
Nagarajan RP, Costello JF. Nagarajan RP, et al. Among authors: costello jf. Semin Cancer Biol. 2009 Jun;19(3):188-97. doi: 10.1016/j.semcancer.2009.02.005. Epub 2009 Feb 20. Semin Cancer Biol. 2009. PMID: 19429483 Review.
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.
Chen R, Nishimura MC, Bumbaca SM, Kharbanda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modrusan Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, James CD, VandenBerg SR, Costello JF, Moorefield S, Cowdrey CJ, Prados M, Phillips HS. Chen R, et al. Among authors: costello jf. Cancer Cell. 2010 Apr 13;17(4):362-75. doi: 10.1016/j.ccr.2009.12.049. Cancer Cell. 2010. PMID: 20385361 Free article.
Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge.
Sturm D, Bender S, Jones DT, Lichter P, Grill J, Becher O, Hawkins C, Majewski J, Jones C, Costello JF, Iavarone A, Aldape K, Brennan CW, Jabado N, Pfister SM. Sturm D, et al. Among authors: costello jf. Nat Rev Cancer. 2014 Feb;14(2):92-107. doi: 10.1038/nrc3655. Nat Rev Cancer. 2014. PMID: 24457416 Free PMC article. Review.
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma.
Butowski N, Chang SM, Lamborn KR, Polley MY, Pieper R, Costello JF, Vandenberg S, Parvataneni R, Nicole A, Sneed PK, Clarke J, Hsieh E, Costa BM, Reis RM, Hristova-Kazmierski M, Nicol SJ, Thornton DE, Prados MD. Butowski N, et al. Among authors: costello jf. Neuro Oncol. 2011 Dec;13(12):1331-8. doi: 10.1093/neuonc/nor130. Epub 2011 Sep 6. Neuro Oncol. 2011. PMID: 21896554 Free PMC article. Clinical Trial.
253 results