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Single-cell RNA sequencing and spatial transcriptomics reveal cancer-associated fibroblasts in glioblastoma with protumoral effects.
Jain S, Rick JW, Joshi RS, Beniwal A, Spatz J, Gill S, Chang AC, Choudhary N, Nguyen AT, Sudhir S, Chalif EJ, Chen JS, Chandra A, Haddad AF, Wadhwa H, Shah SS, Choi S, Hayes JL, Wang L, Yagnik G, Costello JF, Diaz A, Heiland DH, Aghi MK. Jain S, et al. Among authors: yagnik g. J Clin Invest. 2023 Mar 1;133(5):e147087. doi: 10.1172/JCI147087. J Clin Invest. 2023. PMID: 36856115 Free PMC article.
The Phenotypes of Proliferating Glioblastoma Cells Reside on a Single Axis of Variation.
Wang L, Babikir H, Müller S, Yagnik G, Shamardani K, Catalan F, Kohanbash G, Alvarado B, Di Lullo E, Kriegstein A, Shah S, Wadhwa H, Chang SM, Phillips JJ, Aghi MK, Diaz AA. Wang L, et al. Among authors: yagnik g. Cancer Discov. 2019 Dec;9(12):1708-1719. doi: 10.1158/2159-8290.CD-19-0329. Epub 2019 Sep 25. Cancer Discov. 2019. PMID: 31554641 Free PMC article.
Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance.
Chandra A, Jahangiri A, Chen W, Nguyen AT, Yagnik G, Pereira MP, Jain S, Garcia JH, Shah SS, Wadhwa H, Joshi RS, Weiss J, Wolf KJ, Lin JG, Müller S, Rick JW, Diaz AA, Gilbert LA, Kumar S, Aghi MK. Chandra A, et al. Among authors: yagnik g. Cancer Res. 2020 Apr 1;80(7):1498-1511. doi: 10.1158/0008-5472.CAN-19-1305. Epub 2020 Feb 10. Cancer Res. 2020. PMID: 32041837 Free PMC article.
Role of c-Met/β1 integrin complex in the metastatic cascade in breast cancer.
Lau D, Wadhwa H, Sudhir S, Chang AC, Jain S, Chandra A, Nguyen AT, Spatz JM, Pappu A, Shah SS, Cheng J, Safaee MM, Yagnik G, Jahangiri A, Aghi MK. Lau D, et al. Among authors: yagnik g. JCI Insight. 2021 Jun 22;6(12):e138928. doi: 10.1172/jci.insight.138928. JCI Insight. 2021. PMID: 34003803 Free PMC article.
Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer.
Jahangiri A, Nguyen A, Chandra A, Sidorov MK, Yagnik G, Rick J, Han SW, Chen W, Flanigan PM, Schneidman-Duhovny D, Mascharak S, De Lay M, Imber B, Park CC, Matsumoto K, Lu K, Bergers G, Sali A, Weiss WA, Aghi MK. Jahangiri A, et al. Among authors: yagnik g. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8685-E8694. doi: 10.1073/pnas.1701821114. Epub 2017 Sep 26. Proc Natl Acad Sci U S A. 2017. PMID: 28973887 Free PMC article.
Autophagy as a mechanism for anti-angiogenic therapy resistance.
Chandra A, Rick J, Yagnik G, Aghi MK. Chandra A, et al. Among authors: yagnik g. Semin Cancer Biol. 2020 Nov;66:75-88. doi: 10.1016/j.semcancer.2019.08.031. Epub 2019 Aug 28. Semin Cancer Biol. 2020. PMID: 31472232 Free PMC article. Review.
60 results