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Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism.
Upadhyayula PS, Higgins DM, Mela A, Banu M, Dovas A, Zandkarimi F, Patel P, Mahajan A, Humala N, Nguyen TTT, Chaudhary KR, Liao L, Argenziano M, Sudhakar T, Sperring CP, Shapiro BL, Ahmed ER, Kinslow C, Ye LF, Siegelin MD, Cheng S, Soni R, Bruce JN, Stockwell BR, Canoll P. Upadhyayula PS, et al. Among authors: siegelin md. Nat Commun. 2023 Mar 2;14(1):1187. doi: 10.1038/s41467-023-36630-w. Nat Commun. 2023. PMID: 36864031 Free PMC article.
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
Karpel-Massler G, Kast RE, Westhoff MA, Dwucet A, Welscher N, Nonnenmacher L, Hlavac M, Siegelin MD, Wirtz CR, Debatin KM, Halatsch ME. Karpel-Massler G, et al. Among authors: siegelin md. J Neurooncol. 2015 Mar;122(1):21-33. doi: 10.1007/s11060-014-1688-7. Epub 2014 Dec 19. J Neurooncol. 2015. PMID: 25524815
Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro.
Cao Q, Hajosch A, Kast RE, Loehmann C, Hlavac M, Fischer-Posovszky P, Strobel H, Westhoff MA, Siegelin MD, Wirtz CR, Halatsch ME, Karpel-Massler G. Cao Q, et al. Among authors: siegelin md. Br J Cancer. 2024 May;130(8):1365-1376. doi: 10.1038/s41416-024-02608-8. Epub 2024 Feb 23. Br J Cancer. 2024. PMID: 38396172 Free PMC article.
Sorafenib exerts anti-glioma activity in vitro and in vivo.
Siegelin MD, Raskett CM, Gilbert CA, Ross AH, Altieri DC. Siegelin MD, et al. Neurosci Lett. 2010 Jul 12;478(3):165-70. doi: 10.1016/j.neulet.2010.05.009. Epub 2010 May 12. Neurosci Lett. 2010. PMID: 20470863 Free PMC article.
114 results