Van Duyne G - Search Results

1

Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 Å resolution: Routes to inhibitor optimization.

Eilers G, Gupta K, Allen A, Montermoso S, Murali H, Sharp R, Hwang Y, Bushman FD, Van Duyne G. Eilers G, et al. Among authors: van duyne g. PLoS Pathog. 2023 Mar 3;19(3):e1011097. doi: 10.1371/journal.ppat.1011097. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36867659 Free PMC article.

2

Preferential synapsis of loxP sites drives ordered strand exchange in Cre-loxP site-specific recombination.

Ghosh K, Lau CK, Gupta K, Van Duyne GD. Ghosh K, et al. Nat Chem Biol. 2005 Oct;1(5):275-82. doi: 10.1038/nchembio733. Epub 2005 Sep 11. Nat Chem Biol. 2005. PMID: 16408057

3

Structural basis for specificity in the poxvirus topoisomerase.

Perry K, Hwang Y, Bushman FD, Van Duyne GD. Perry K, et al. Mol Cell. 2006 Aug 4;23(3):343-54. doi: 10.1016/j.molcel.2006.06.015. Mol Cell. 2006. PMID: 16885024 Free article.

4

Regulation of catalysis by the smallpox virus topoisomerase.

Hwang Y, Minkah N, Perry K, Van Duyne GD, Bushman FD. Hwang Y, et al. J Biol Chem. 2006 Dec 8;281(49):38052-60. doi: 10.1074/jbc.M608858200. Epub 2006 Oct 10. J Biol Chem. 2006. PMID: 17032643 Free article.

5

Variola virus topoisomerase: DNA cleavage specificity and distribution of sites in Poxvirus genomes.

Minkah N, Hwang Y, Perry K, Van Duyne GD, Hendrickson R, Lefkowitz EJ, Hannenhalli S, Bushman FD. Minkah N, et al. Virology. 2007 Aug 15;365(1):60-9. doi: 10.1016/j.virol.2007.02.037. Epub 2007 Apr 25. Virology. 2007. PMID: 17462694 Free PMC article.

6

Tetrameric structure of a serine integrase catalytic domain.

Yuan P, Gupta K, Van Duyne GD. Yuan P, et al. Structure. 2008 Aug 6;16(8):1275-86. doi: 10.1016/j.str.2008.04.018. Structure. 2008. PMID: 18682229 Free article.

7

Insights from the structure of a smallpox virus topoisomerase-DNA transition state mimic.

Perry K, Hwang Y, Bushman FD, Van Duyne GD. Perry K, et al. Structure. 2010 Jan 13;18(1):127-37. doi: 10.1016/j.str.2009.10.020. Structure. 2010. PMID: 20152159 Free PMC article.

8

Structural properties of HIV integrase. Lens epithelium-derived growth factor oligomers.

Gupta K, Diamond T, Hwang Y, Bushman F, Van Duyne GD. Gupta K, et al. J Biol Chem. 2010 Jun 25;285(26):20303-15. doi: 10.1074/jbc.M110.114413. Epub 2010 Apr 20. J Biol Chem. 2010. PMID: 20406807 Free PMC article.

9

Requirements for catalysis in the Cre recombinase active site.

Gibb B, Gupta K, Ghosh K, Sharp R, Chen J, Van Duyne GD. Gibb B, et al. Nucleic Acids Res. 2010 Sep;38(17):5817-32. doi: 10.1093/nar/gkq384. Epub 2010 May 12. Nucleic Acids Res. 2010. PMID: 20462863 Free PMC article.

10

Solution structure of the core SMN-Gemin2 complex.

Sarachan KL, Valentine KG, Gupta K, Moorman VR, Gledhill JM Jr, Bernens M, Tommos C, Wand AJ, Van Duyne GD. Sarachan KL, et al. Among authors: van duyne gd. Biochem J. 2012 Aug 1;445(3):361-70. doi: 10.1042/BJ20120241. Biochem J. 2012. PMID: 22607171 Free PMC article.

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