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High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults.
Roider J, Maehara T, Ngoepe A, Ramsuran D, Muenchhoff M, Adland E, Aicher T, Kazer SW, Jooste P, Karim F, Kuhn W, Shalek AK, Ndung'u T, Morris L, Moore PL, Pillai S, Kløverpris H, Goulder P, Leslie A. Roider J, et al. Among authors: karim f. Front Immunol. 2018 Sep 12;9:1975. doi: 10.3389/fimmu.2018.01975. eCollection 2018. Front Immunol. 2018. PMID: 30258437 Free PMC article. Clinical Trial.
Contrasting Inflammatory Signatures in Peripheral Blood and Bronchoalveolar Cells Reveal Compartment-Specific Effects of HIV Infection.
Muema DM, Mthembu M, Schiff AE, Singh U, Corleis B, Chen D, Bassett T, Rasehlo SS, Nyamande K, Khan DF, Maharaj P, Mitha M, Suleman M, Mhlane Z, Naidoo T, Ramjit D, Karim F, Kwon DS, Ndung'u T, Wong EB. Muema DM, et al. Among authors: karim f. Front Immunol. 2020 May 19;11:864. doi: 10.3389/fimmu.2020.00864. eCollection 2020. Front Immunol. 2020. PMID: 32508817 Free PMC article.
Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy.
Singh A, Kazer SW, Roider J, Krista KC, Millar J, Asowata OE, Ngoepe A, Ramsuran D, Fardoos R, Ardain A, Muenchhoff M, Kuhn W, Karim F, Ndung'u T, Shalek AK, Goulder P, Leslie A, Kløverpris HN. Singh A, et al. Among authors: karim f. Cell Rep. 2020 Sep 15;32(11):108153. doi: 10.1016/j.celrep.2020.108153. Cell Rep. 2020. PMID: 32937142 Free PMC article.
Escape of SARS-CoV-2 501Y.V2 from neutralization by convalescent plasma.
Cele S, Gazy I, Jackson L, Hwa SH, Tegally H, Lustig G, Giandhari J, Pillay S, Wilkinson E, Naidoo Y, Karim F, Ganga Y, Khan K, Bernstein M, Balazs AB, Gosnell BI, Hanekom W, Moosa MS; Network for Genomic Surveillance in South Africa; COMMIT-KZN Team; Lessells RJ, de Oliveira T, Sigal A. Cele S, et al. Among authors: karim f. Nature. 2021 May;593(7857):142-146. doi: 10.1038/s41586-021-03471-w. Epub 2021 Mar 29. Nature. 2021. PMID: 33780970 Free PMC article.
MR1-Restricted MAIT Cells From The Human Lung Mucosal Surface Have Distinct Phenotypic, Functional, and Transcriptomic Features That Are Preserved in HIV Infection.
Khuzwayo S, Mthembu M, Meermeier EW, Prakadan SM, Kazer SW, Bassett T, Nyamande K, Khan DF, Maharaj P, Mitha M, Suleman M, Mhlane Z, Ramjit D, Karim F, Shalek AK, Lewinsohn DM, Ndung'u T, Wong EB. Khuzwayo S, et al. Among authors: karim f. Front Immunol. 2021 Apr 9;12:631410. doi: 10.3389/fimmu.2021.631410. eCollection 2021. Front Immunol. 2021. PMID: 33897687 Free PMC article.
HIV infection drives interferon signaling within intestinal SARS-CoV-2 target cells.
Fardoos R, Asowata OE, Herbert N, Nyquist SK, Zungu Y, Singh A, Ngoepe A, Mbano IM, Mthabela N, Ramjit D, Karim F, Kuhn W, Madela FG, Manzini VT, Anderson F, Berger B, Pers TH, Shalek AK, Leslie A, Kløverpris HN. Fardoos R, et al. Among authors: karim f. JCI Insight. 2021 Aug 23;6(16):e148920. doi: 10.1172/jci.insight.148920. JCI Insight. 2021. PMID: 34252054 Free PMC article.
Similar Antibody Responses Against Severe Acute Respiratory Syndrome Coronavirus 2 in Individuals Living Without and With Human Immunodeficiency Virus on Antiretroviral Therapy During the First South African Infection Wave.
Snyman J, Hwa SH, Krause R, Muema D, Reddy T, Ganga Y, Karim F, Leslie A, Sigal A, Ndung'u T; COVID-19 Mechanisms and Multi-omics at the Intersection of TB and HIV in KwaZulu-Natal (COMMIT-KZN Team). Snyman J, et al. Among authors: karim f. Clin Infect Dis. 2022 Aug 24;75(1):e249-e256. doi: 10.1093/cid/ciab758. Clin Infect Dis. 2022. PMID: 34472583 Free PMC article.
HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave.
Karim F, Gazy I, Cele S, Zungu Y, Krause R, Bernstein M, Khan K, Ganga Y, Rodel H, Mthabela N, Mazibuko M, Muema D, Ramjit D, Ndung'u T, Hanekom W, Gosnell B; COMMIT-KZN Team; Lessells RJ, Wong EB, de Oliveira T, Moosa MS, Lustig G, Leslie A, Kløverpris H, Sigal A. Karim F, et al. Elife. 2021 Oct 5;10:e67397. doi: 10.7554/eLife.67397. Elife. 2021. PMID: 34608862 Free PMC article.
658 results