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Autoantibodies against chemokines post-SARS-CoV-2 infection correlate with disease course.
Muri J, Cecchinato V, Cavalli A, Shanbhag AA, Matkovic M, Biggiogero M, Maida PA, Moritz J, Toscano C, Ghovehoud E, Furlan R, Barbic F, Voza A, De Nadai G, Cervia C, Zurbuchen Y, Taeschler P, Murray LA, Danelon-Sargenti G, Moro S, Gong T, Piffaretti P, Bianchini F, Crivelli V, Podešvová L, Pedotti M, Jarrossay D, Sgrignani J, Thelen S, Uhr M, Bernasconi E, Rauch A, Manzo A, Ciurea A, Rocchi MBL, Varani L, Moser B, Bottazzi B, Thelen M, Fallon BA, Boyman O, Mantovani A, Garzoni C, Franzetti-Pellanda A, Uguccioni M, Robbiani DF. Muri J, et al. Among authors: pedotti m. Nat Immunol. 2023 Apr;24(4):604-611. doi: 10.1038/s41590-023-01445-w. Epub 2023 Mar 6. Nat Immunol. 2023. PMID: 36879067 Free PMC article.
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4.
Schiraldi M, Raucci A, Muñoz LM, Livoti E, Celona B, Venereau E, Apuzzo T, De Marchis F, Pedotti M, Bachi A, Thelen M, Varani L, Mellado M, Proudfoot A, Bianchi ME, Uguccioni M. Schiraldi M, et al. Among authors: pedotti m. J Exp Med. 2012 Mar 12;209(3):551-63. doi: 10.1084/jem.20111739. Epub 2012 Feb 27. J Exp Med. 2012. PMID: 22370717 Free PMC article.
Epitope mapping by solution NMR spectroscopy.
Bardelli M, Livoti E, Simonelli L, Pedotti M, Moraes A, Valente AP, Varani L. Bardelli M, et al. Among authors: pedotti m. J Mol Recognit. 2015 Jun;28(6):393-400. doi: 10.1002/jmr.2454. Epub 2015 Feb 27. J Mol Recognit. 2015. PMID: 25726811
SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface.
Bertoglio F, Meier D, Langreder N, Steinke S, Rand U, Simonelli L, Heine PA, Ballmann R, Schneider KT, Roth KDR, Ruschig M, Riese P, Eschke K, Kim Y, Schäckermann D, Pedotti M, Kuhn P, Zock-Emmenthal S, Wöhrle J, Kilb N, Herz T, Becker M, Grasshoff M, Wenzel EV, Russo G, Kröger A, Brunotte L, Ludwig S, Fühner V, Krämer SD, Dübel S, Varani L, Roth G, Čičin-Šain L, Schubert M, Hust M. Bertoglio F, et al. Among authors: pedotti m. Nat Commun. 2021 Mar 11;12(1):1577. doi: 10.1038/s41467-021-21609-2. Nat Commun. 2021. PMID: 33707427 Free PMC article.
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
De Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Cassaniti I, Percivalle E, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Di Girolamo S, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Sammartino JC, Giardina F, Gaiarsa S, Pan-Hammarström Q, Barnes CO, Bjorkman PJ, Calzolai L, Piralla A, Baldanti F, Nussenzweig MC, Bieniasz PD, Hatziioannou T, Prochazka J, Sedlacek R, Robbiani DF, Ruzek D, Varani L. De Gasparo R, et al. Among authors: pedotti m. Nature. 2021 May;593(7859):424-428. doi: 10.1038/s41586-021-03461-y. Epub 2021 Mar 25. Nature. 2021. PMID: 33767445
36 results