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Structure-based discovery of CFTR potentiators and inhibitors.
bioRxiv [Preprint]. 2024 Mar 11:2023.09.09.557002. doi: 10.1101/2023.09.09.557002.
bioRxiv. 2024.
PMID: 37745391
Free PMC article.
Preprint.
A macrocyclic peptide inhibitor traps MRP1 in a catalytically incompetent conformation.
Pietz HL, Abbas A, Johnson ZL, Oldham ML, Suga H, Chen J.
Pietz HL, et al.
Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2220012120. doi: 10.1073/pnas.2220012120. Epub 2023 Mar 9.
Proc Natl Acad Sci U S A. 2023.
PMID: 36893260
Free PMC article.
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Serum and Cervicovaginal Fluid Antibody Profiling in Herpes Simplex Virus-Seronegative Recipients of the HSV529 Vaccine.
Wang K, Dropulic L, Bozekowski J, Pietz HL, Jegaskanda S, Dowdell K, Vogel JS, Garabedian D, Oestreich M, Nguyen H, Ali MA, Lumbard K, Hunsberger S, Reifert J, Haynes WA, Sawyer JR, Shon JC, Daugherty PS, Cohen JI.
Wang K, et al. Among authors: pietz hl.
J Infect Dis. 2021 Nov 16;224(9):1509-1519. doi: 10.1093/infdis/jiab139.
J Infect Dis. 2021.
PMID: 33718970
Free PMC article.
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A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus (HSV) Type 2 Vaccine, HSV529, in Adults With or Without HSV Infection.
Dropulic LK, Oestreich MC, Pietz HL, Laing KJ, Hunsberger S, Lumbard K, Garabedian D, Turk SP, Chen A, Hornung RL, Seshadri C, Smith MT, Hosken NA, Phogat S, Chang LJ, Koelle DM, Wang K, Cohen JI.
Dropulic LK, et al. Among authors: pietz hl.
J Infect Dis. 2019 Aug 9;220(6):990-1000. doi: 10.1093/infdis/jiz225.
J Infect Dis. 2019.
PMID: 31058977
Free PMC article.
Clinical Trial.
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Pharmacodynamics of anti-HIV gene therapy using viral vectors and targeted endonucleases.
Roychoudhury P, De Silva Feelixge HS, Pietz HL, Stone D, Jerome KR, Schiffer JT.
Roychoudhury P, et al. Among authors: pietz hl.
J Antimicrob Chemother. 2016 Aug;71(8):2089-99. doi: 10.1093/jac/dkw104. Epub 2016 Apr 18.
J Antimicrob Chemother. 2016.
PMID: 27090632
Free PMC article.
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Detection of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy.
De Silva Feelixge HS, Stone D, Pietz HL, Roychoudhury P, Greninger AL, Schiffer JT, Aubert M, Jerome KR.
De Silva Feelixge HS, et al. Among authors: pietz hl.
Antiviral Res. 2016 Feb;126:90-8. doi: 10.1016/j.antiviral.2015.12.007. Epub 2015 Dec 22.
Antiviral Res. 2016.
PMID: 26718067
Free PMC article.
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