Khvorova A - Search Results

1

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.

Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Hariharan VN, et al. Among authors: khvorova a. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219523120. doi: 10.1073/pnas.2219523120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893269 Free PMC article.

2

Mimics of yeast tRNAAsp and their recognition by aspartyl-tRNA synthetase.

Wolfson AD, Khvorova AM, Sauter C, Florentz C, Giegé R. Wolfson AD, et al. Among authors: khvorova am. Biochemistry. 1999 Sep 14;38(37):11926-32. doi: 10.1021/bi9908383. Biochemistry. 1999. PMID: 10508395

3

Binding of manganese(II) to a tertiary stabilized hammerhead ribozyme as studied by electron paramagnetic resonance spectroscopy.

Kisseleva N, Khvorova A, Westhof E, Schiemann O. Kisseleva N, et al. Among authors: khvorova a. RNA. 2005 Jan;11(1):1-6. doi: 10.1261/rna.7127105. RNA. 2005. PMID: 15611296 Free PMC article.

4

[Specific aminoacylation of oligo U-CCA lysyl-tRNA-synthetase molecules].

Khvorova AM, Motorin IuA, Vol'fson AD, Gladilin KL. Khvorova AM, et al. Dokl Akad Nauk. 1992;325(1):179-82. Dokl Akad Nauk. 1992. PMID: 1425198 Russian. No abstract available.

5

Synthetic tRNALys,3 as the replication primer for the HIV-1HXB2 and HIV-1Mal genomes.

Miller JT, Khvorova A, Scaringe SA, Le Grice SF. Miller JT, et al. Among authors: khvorova a. Nucleic Acids Res. 2004 Sep 1;32(15):4687-95. doi: 10.1093/nar/gkh813. Print 2004. Nucleic Acids Res. 2004. PMID: 15342789 Free PMC article.

6

Artificial tertiary motifs stabilize trans-cleaving hammerhead ribozymes under conditions of submillimolar divalent ions and high temperatures.

Saksmerprome V, Roychowdhury-Saha M, Jayasena S, Khvorova A, Burke DH. Saksmerprome V, et al. Among authors: khvorova a. RNA. 2004 Dec;10(12):1916-24. doi: 10.1261/rna.7159504. RNA. 2004. PMID: 15547137 Free PMC article.

7

New competition in RNA regulation.

Khvorova A, Wolfson A. Khvorova A, et al. Nat Biotechnol. 2012 Jan 9;30(1):58-9. doi: 10.1038/nbt.2092. Nat Biotechnol. 2012. PMID: 22231098 No abstract available.

8

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets.

Birmingham A, Anderson EM, Reynolds A, Ilsley-Tyree D, Leake D, Fedorov Y, Baskerville S, Maksimova E, Robinson K, Karpilow J, Marshall WS, Khvorova A. Birmingham A, et al. Among authors: khvorova a. Nat Methods. 2006 Mar;3(3):199-204. doi: 10.1038/nmeth854. Nat Methods. 2006. PMID: 16489337

9

Off-target effects by siRNA can induce toxic phenotype.

Fedorov Y, Anderson EM, Birmingham A, Reynolds A, Karpilow J, Robinson K, Leake D, Marshall WS, Khvorova A. Fedorov Y, et al. Among authors: khvorova a. RNA. 2006 Jul;12(7):1188-96. doi: 10.1261/rna.28106. Epub 2006 May 8. RNA. 2006. PMID: 16682561 Free PMC article.

10

Functional siRNAs and miRNAs exhibit strand bias.

Khvorova A, Reynolds A, Jayasena SD. Khvorova A, et al. Cell. 2003 Oct 17;115(2):209-16. doi: 10.1016/s0092-8674(03)00801-8. Cell. 2003. PMID: 14567918 Free article.

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