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Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.
Hariharan VN, Shin M, Chang CW, O'Reilly D, Biscans A, Yamada K, Guo Z, Somasundaran M, Tang Q, Monopoli K, Krishnamurthy PM, Devi G, McHugh N, Cooper DA, Echeverria D, Cruz J, Chan IL, Liu P, Lim SY, McConnell J, Singh SP, Hildebrand S, Sousa J, Davis SM, Kennedy Z, Ferguson C, Godinho BMDC, Thillier Y, Caiazzi J, Ly S, Muhuri M, Kelly K, Humphries F, Cousineau A, Parsi KM, Li Q, Wang Y, Maehr R, Gao G, Korkin D, McDougall WM, Finberg RW, Fitzgerald KA, Wang JP, Watts JK, Khvorova A. Hariharan VN, et al. Among authors: li q. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2219523120. doi: 10.1073/pnas.2219523120. Epub 2023 Mar 9. Proc Natl Acad Sci U S A. 2023. PMID: 36893269 Free PMC article.
Study of the Effects of Several SARS-CoV-2 Structural Proteins on Antiviral Immunity.
Yue R, Zeng F, Ma D, Meng Z, Li X, Zhang Z, Zhang H, Li Q, Xu L, Niu Z, Li D, Liao Y, Jiang G, Yu L, Zhao H, Zhang Y, Liu L, Li Q. Yue R, et al. Among authors: li d, li x, li q. Vaccines (Basel). 2023 Feb 23;11(3):524. doi: 10.3390/vaccines11030524. Vaccines (Basel). 2023. PMID: 36992107 Free PMC article.
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