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Halofuginone for non-hospitalized adult patients with COVID-19 a multicenter, randomized placebo-controlled phase 2 trial. The HALOS trial.
Tomazini BM, Tramujas L, Medrado FA Junior, Gomes SPDC, Negrelli KL, Murinize GS, Santos RHN, Vianna BMP, Piotto BF, Veiga TS, Santos BRD, Peneluppi Horak AC, Lemos OMC, Lopes MA, Olicheski BB, Campones DL, Peixoto LAA, Basilio ADAC, Gebara OCE, Lopes ATA, Saconato H, Valeis N, Miranda TA, Laranjeira LN, Santucci EV, Carlin AF, Esko JD, Gordts PLSM, Tsimikas S, Cavalcanti AB. Tomazini BM, et al. Among authors: lopes ata. PLoS One. 2024 Feb 23;19(2):e0299197. doi: 10.1371/journal.pone.0299197. eCollection 2024. PLoS One. 2024. PMID: 38394069 Free PMC article. Clinical Trial.
Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn trial.
Maia IS, Marcadenti A, Veiga VC, Miranda TA, Gomes SPC, Carollo MBS, Negrelli KL, Gomes JO, Tramujas L, Abreu-Silva EO, Westphal GA, Fernandes RP, Horta JGA, Oliveira DC, Flato UAP, Paoliello RCR, Fernandes C, Zandonai CL, Coelho JC, Barros WC, Lemos JC, Bolan RS, Dutra MM, Gebara OCE, Lopes ATA, Alencar Filho MS, Arraes JA, Hamamoto VA, Hernandes ME, Golin NA, Santos TM, Santos RHN, Damiani LP, Zampieri FG, Gesto J, Machado FR, Rosa RG, Azevedo LCP, Avezum A, Lopes RD, Souza TML, Berwanger O, Cavalcanti AB; BRICNet. Maia IS, et al. Among authors: lopes ata. Lancet Reg Health Am. 2023 Apr;20:100466. doi: 10.1016/j.lana.2023.100466. Epub 2023 Mar 8. Lancet Reg Health Am. 2023. PMID: 36908503 Free PMC article.
Hydroxychloroquine plus azithromycin early treatment of mild COVID-19 in an outpatient setting: a randomized, double-blinded, placebo-controlled clinical trial evaluating viral clearance.
Rodrigues C, Freitas-Santos RS, Levi JE, Senerchia AA, Lopes ATA, Santos SR, Siciliano RF, Pierrotti LC. Rodrigues C, et al. Among authors: lopes ata. Int J Antimicrob Agents. 2021 Nov;58(5):106428. doi: 10.1016/j.ijantimicag.2021.106428. Epub 2021 Aug 25. Int J Antimicrob Agents. 2021. PMID: 34454044 Free PMC article. Clinical Trial.