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297 results

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Germline genetic regulation of the colorectal tumor immune microenvironment.
Schmit SL, Tsai YY, Bonner JD, Sanz-Pamplona R, Joshi AD, Ugai T, Lindsey SS, Melas M, McDonnell KJ, Idos GE, Walker CP, Qu C, Kast WM, Da Silva DM, Glickman JN, Chan AT, Giannakis M, Nowak JA, Rennert HS, Robins HS, Ogino S, Greenson JK, Moreno V, Rennert G, Gruber SB. Schmit SL, et al. Among authors: glickman jn. BMC Genomics. 2024 Apr 25;25(1):409. doi: 10.1186/s12864-024-10295-1. BMC Genomics. 2024. PMID: 38664626 Free PMC article.
Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055.
Michino M, Khan TA, Miller MW, Fukase Y, Vendome J, Adura C, Glickman JF, Liu Y, Wan L, Allis CD, Stamford AW, Meinke PT, Renzetti LM, Kargman S, Liverton NJ, Huggins DJ. Michino M, et al. Among authors: glickman jf. ACS Med Chem Lett. 2024 Mar 12;15(4):524-532. doi: 10.1021/acsmedchemlett.4c00016. eCollection 2024 Apr 11. ACS Med Chem Lett. 2024. PMID: 38628784
Integrated annotation prioritizes metabolites with bioactivity in inflammatory bowel disease.
Bhosle A, Bae S, Zhang Y, Chun E, Avila-Pacheco J, Geistlinger L, Pishchany G, Glickman JN, Michaud M, Waldron L, Clish CB, Xavier RJ, Vlamakis H, Franzosa EA, Garrett WS, Huttenhower C. Bhosle A, et al. Among authors: glickman jn. Mol Syst Biol. 2024 Apr;20(4):338-361. doi: 10.1038/s44320-024-00027-8. Epub 2024 Mar 11. Mol Syst Biol. 2024. PMID: 38467837 Free PMC article.
High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease.
Krumm CS, Landzberg RS, Ramos-Espiritu L, Adura C, Liu X, Acuna M, Xie Y, Xu X, Tillman MC, Li Y, Glickman JF, Ortlund EA, Ginn JD, Cohen DE. Krumm CS, et al. Among authors: glickman jf. Mol Metab. 2023 Dec;78:101832. doi: 10.1016/j.molmet.2023.101832. Epub 2023 Oct 30. Mol Metab. 2023. PMID: 38403978 Free PMC article.
Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS. Huang YH, et al. Among authors: glickman jn. Nature. 2024 Feb;626(8001):E19. doi: 10.1038/s41586-024-07164-y. Nature. 2024. PMID: 38336833 No abstract available.
Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists.
Xie W, Lama L, Yang X, Kuryavyi V, Bhattacharya S, Nudelman I, Yang G, Ouerfelli O, Glickman JF, Jones RA, Tuschl T, Patel DJ. Xie W, et al. Among authors: glickman jf. Cell Chem Biol. 2023 Nov 16;30(11):1366-1376.e7. doi: 10.1016/j.chembiol.2023.07.002. Epub 2023 Aug 2. Cell Chem Biol. 2023. PMID: 37536341
Free heme exacerbates colonic injury induced by anti-cancer therapy.
Seika P, Janikova M, Asokan S, Janovicova L, Csizmadia E, O'Connell M, Robson SC, Glickman J, Wegiel B. Seika P, et al. Among authors: glickman j. Front Immunol. 2023 Jun 5;14:1184105. doi: 10.3389/fimmu.2023.1184105. eCollection 2023. Front Immunol. 2023. PMID: 37342339 Free PMC article.
AI-based histologic scoring enables automated and reproducible assessment of enrollment criteria and endpoints in NASH clinical trials.
Iyer JS, Pokkalla H, Biddle-Snead C, Carrasco-Zevallos O, Lin M, Shanis Z, Le Q, Juyal D, Pouryahya M, Pedawi A, Hoffman S, Elliott H, Leidal K, Myers RP, Chung C, Billin AN, Watkins TR, Resnick M, Wack K, Glickman J, Burt AD, Loomba R, Sanyal AJ, Montalto MC, Beck AH, Taylor-Weiner A, Wapinski I. Iyer JS, et al. Among authors: glickman j. medRxiv [Preprint]. 2023 Apr 25:2023.04.20.23288534. doi: 10.1101/2023.04.20.23288534. medRxiv. 2023. PMID: 37162870 Free PMC article. Preprint.
297 results