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Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates.
Bioorg Med Chem Lett. 2023 Jul 15;91:129348. doi: 10.1016/j.bmcl.2023.129348. Epub 2023 May 20.
Bioorg Med Chem Lett. 2023.
PMID: 37217025
An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.
Weisser NE, Sanches M, Escobar-Cabrera E, O'Toole J, Whalen E, Chan PWY, Wickman G, Abraham L, Choi K, Harbourne B, Samiotakis A, Rojas AH, Volkers G, Wong J, Atkinson CE, Baardsnes J, Worrall LJ, Browman D, Smith EE, Baichoo P, Cheng CW, Guedia J, Kang S, Mukhopadhyay A, Newhook L, Ohrn A, Raghunatha P, Zago-Schmitt M, Schrag JD, Smith J, Zwierzchowski P, Scurll JM, Fung V, Black S, Strynadka NCJ, Gold MR, Presta LG, Ng G, Dixit S.
Weisser NE, et al. Among authors: guedia j.
Nat Commun. 2023 Mar 13;14(1):1394. doi: 10.1038/s41467-023-37029-3.
Nat Commun. 2023.
PMID: 36914633
Free PMC article.
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HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system.
Guedia J, Brun P, Bhave S, Fitting S, Kang M, Dewey WL, Hauser KF, Akbarali HI.
Guedia J, et al.
Sci Rep. 2016 Aug 5;6:31203. doi: 10.1038/srep31203.
Sci Rep. 2016.
PMID: 27491828
Free PMC article.
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