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Page 1
FGFR inhibition augments anti-PD-1 efficacy in murine FGFR3-mutant bladder cancer by abrogating immunosuppression.
Okato A, Utsumi T, Ranieri M, Zheng X, Zhou M, Pereira LD, Chen T, Kita Y, Wu D, Hyun H, Lee H, Gdowski AS, Raupp JD, Clark-Garvey S, Manocha U, Chafitz A, Sherman F, Stephens J, Rose TL, Milowsky MI, Wobker SE, Serody JS, Damrauer JS, Wong KK, Kim WY. Okato A, et al. Among authors: manocha u. J Clin Invest. 2024 Jan 16;134(2):e169241. doi: 10.1172/JCI169241. J Clin Invest. 2024. PMID: 38226620 Free PMC article.
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.
Shi L, Shen W, Davis MI, Kong K, Vu P, Saha SK, Adil R, Kreuzer J, Egan R, Lee TD, Greninger P, Shrimp JH, Zhao W, Wei TY, Zhou M, Eccleston J, Sussman J, Manocha U, Weerasekara V, Kondo H, Vijay V, Wu MJ, Kearney SE, Ho J, McClanaghan J, Murchie E, Crowther GS, Patnaik S, Boxer MB, Shen M, Ting DT, Kim WY, Stanger BZ, Deshpande V, Ferrone CR, Benes CH, Haas W, Hall MD, Bardeesy N. Shi L, et al. Among authors: manocha u. Nat Cancer. 2023 Mar;4(3):365-381. doi: 10.1038/s43018-023-00523-0. Epub 2023 Mar 13. Nat Cancer. 2023. PMID: 36914816 Free PMC article.
ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer.
Fang W, Liao C, Shi R, Simon JM, Ptacek TS, Zurlo G, Ye Y, Han L, Fan C, Bao L, Ortiz CL, Lin HR, Manocha U, Luo W, Peng Y, Kim WY, Yang LW, Zhang Q. Fang W, et al. Among authors: manocha u. Elife. 2021 Nov 15;10:e70412. doi: 10.7554/eLife.70412. Elife. 2021. PMID: 34779768 Free PMC article.
Entinostat induces antitumor immune responses through immune editing of tumor neoantigens.
Truong AS, Zhou M, Krishnan B, Utsumi T, Manocha U, Stewart KG, Beck W, Rose TL, Milowsky MI, He X, Smith CC, Bixby LM, Perou CM, Wobker SE, Bailey ST, Vincent BG, Kim WY. Truong AS, et al. Among authors: manocha u. J Clin Invest. 2021 Aug 16;131(16):e138560. doi: 10.1172/JCI138560. J Clin Invest. 2021. PMID: 34396985 Free PMC article.
Development and validation of a NanoString BASE47 bladder cancer gene classifier.
Kardos J, Rose TL, Manocha U, Wobker SE, Damrauer JS, Bivalaqua TJ, Kates M, Moore KJ, Parker JS, Kim WY. Kardos J, et al. Among authors: manocha u. PLoS One. 2020 Dec 17;15(12):e0243935. doi: 10.1371/journal.pone.0243935. eCollection 2020. PLoS One. 2020. PMID: 33332422 Free PMC article.
Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy.
Saito R, Smith CC, Utsumi T, Bixby LM, Kardos J, Wobker SE, Stewart KG, Chai S, Manocha U, Byrd KM, Damrauer JS, Williams SE, Vincent BG, Kim WY. Saito R, et al. Among authors: manocha u. Cancer Res. 2018 Jul 15;78(14):3954-3968. doi: 10.1158/0008-5472.CAN-18-0173. Epub 2018 May 21. Cancer Res. 2018. PMID: 29784854 Free PMC article.
MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma.
Bailey ST, Smith AM, Kardos J, Wobker SE, Wilson HL, Krishnan B, Saito R, Lee HJ, Zhang J, Eaton SC, Williams LA, Manocha U, Peters DJ, Pan X, Carroll TJ, Felsher DW, Walter V, Zhang Q, Parker JS, Yeh JJ, Moffitt RA, Leung JY, Kim WY. Bailey ST, et al. Among authors: manocha u. Nat Commun. 2017 Jun 8;8:15770. doi: 10.1038/ncomms15770. Nat Commun. 2017. PMID: 28593993 Free PMC article.