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An integrated single cell and spatial transcriptomic map of human white adipose tissue.
Massier L, Jalkanen J, Elmastas M, Zhong J, Wang T, Nono Nankam PA, Frendo-Cumbo S, Bäckdahl J, Subramanian N, Sekine T, Kerr AG, Tseng BTP, Laurencikiene J, Buggert M, Lourda M, Kublickiene K, Bhalla N, Andersson A, Valsesia A, Astrup A, Blaak EE, Ståhl PL, Viguerie N, Langin D, Wolfrum C, Blüher M, Rydén M, Mejhert N. Massier L, et al. Among authors: sekine t. Nat Commun. 2023 Mar 15;14(1):1438. doi: 10.1038/s41467-023-36983-2. Nat Commun. 2023. PMID: 36922516 Free PMC article.
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation.
Sandberg JT, Varnaitė R, Christ W, Chen P, Muvva JR, Maleki KT, García M, Dzidic M, Folkesson E, Skagerberg M, Ahlén G, Frelin L, Sällberg M, Eriksson LI, Rooyackers O, Sönnerborg A, Buggert M, Björkström NK, Aleman S, Strålin K, Klingström J, Ljunggren HG, Blom K, Gredmark-Russ S; Karolinska COVID‐19 Study Group. Sandberg JT, et al. Clin Transl Immunology. 2021 Jul 5;10(7):e1306. doi: 10.1002/cti2.1306. eCollection 2021. Clin Transl Immunology. 2021. PMID: 34257967 Free PMC article.
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox.
Adamo S, Gao Y, Sekine T, Mily A, Wu J, Storgärd E, Westergren V, Filén F, Treutiger CJ, Sandberg JK, Sällberg M, Bergman P, Llewellyn-Lacey S, Ljunggren HG, Price DA, Ekström AM, Sette A, Grifoni A, Buggert M. Adamo S, et al. Among authors: sekine t. Cell Host Microbe. 2023 Jun 14;31(6):928-936.e4. doi: 10.1016/j.chom.2023.04.015. Epub 2023 Apr 25. Cell Host Microbe. 2023. PMID: 37236191 Free PMC article.
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies.
Kammann T, Gorin JB, Parrot T, Gao Y, Ponzetta A, Emgård J, Maleki KT, Sekine T, Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S, Rooyackers O, Skagerberg M, Eriksson LI, Norrby-Teglund A, Mak JYW, Fairlie DP, Björkström NK, Klingström J, Ljunggren HG, Aleman S, Buggert M, Strålin K, Sandberg JK. Kammann T, et al. Among authors: sekine t. J Immunol. 2024 Feb 1;212(3):389-396. doi: 10.4049/jimmunol.2300639. J Immunol. 2024. PMID: 38117799 Free PMC article.
MAIT cell activation and dynamics associated with COVID-19 disease severity.
Parrot T, Gorin JB, Ponzetta A, Maleki KT, Kammann T, Emgård J, Perez-Potti A, Sekine T, Rivera-Ballesteros O; Karolinska COVID-19 Study Group; Gredmark-Russ S, Rooyackers O, Folkesson E, Eriksson LI, Norrby-Teglund A, Ljunggren HG, Björkström NK, Aleman S, Buggert M, Klingström J, Strålin K, Sandberg JK. Parrot T, et al. Among authors: sekine t. Sci Immunol. 2020 Sep 28;5(51):eabe1670. doi: 10.1126/sciimmunol.abe1670. Sci Immunol. 2020. PMID: 32989174 Free PMC article.
A genetics-led approach defines the drug target landscape of 30 immune-related traits.
Fang H; ULTRA-DD Consortium; De Wolf H, Knezevic B, Burnham KL, Osgood J, Sanniti A, Lledó Lara A, Kasela S, De Cesco S, Wegner JK, Handunnetthi L, McCann FE, Chen L, Sekine T, Brennan PE, Marsden BD, Damerell D, O'Callaghan CA, Bountra C, Bowness P, Sundström Y, Milani L, Berg L, Göhlmann HW, Peeters PJ, Fairfax BP, Sundström M, Knight JC. Fang H, et al. Among authors: sekine t. Nat Genet. 2019 Jul;51(7):1082-1091. doi: 10.1038/s41588-019-0456-1. Epub 2019 Jun 28. Nat Genet. 2019. PMID: 31253980 Free PMC article.
miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis.
Chen L, Al-Mossawi MH, Ridley A, Sekine T, Hammitzsch A, de Wit J, Simone D, Shi H, Penkava F, Kurowska-Stolarska M, Pulyakhina I, Knight JC, Kim TJ, Bowness P. Chen L, et al. Among authors: sekine t. Ann Rheum Dis. 2017 Mar;76(3):620-625. doi: 10.1136/annrheumdis-2016-210175. Epub 2016 Dec 30. Ann Rheum Dis. 2017. PMID: 28039186
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19.
Strunz B, Maucourant C, Mehta A, Wan H, Du L, Sun D, Chen P, Nordlander A, Gao Y, Cornillet M, Bister J, Kvedaraite E, Christ W, Klingström J, Geanon D, Parke Å, Ekwall-Larson A, Rivino L, MacAry PA, Aleman S, Buggert M, Ljunggren HG, Pan-Hammarström Q, Lund-Johansen F, Strålin K, Björkström NK; Karolinska KI/K COVID-19 Study Group. Strunz B, et al. J Infect Dis. 2024 Feb 29:jiae036. doi: 10.1093/infdis/jiae036. Online ahead of print. J Infect Dis. 2024. PMID: 38421006
856 results