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Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.
Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ. Tam HH, et al. Among authors: melo mb. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6639-E6648. doi: 10.1073/pnas.1606050113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702895 Free PMC article.
Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
Cirelli KM, Carnathan DG, Nogal B, Martin JT, Rodriguez OL, Upadhyay AA, Enemuo CA, Gebru EH, Choe Y, Viviano F, Nakao C, Pauthner MG, Reiss S, Cottrell CA, Smith ML, Bastidas R, Gibson W, Wolabaugh AN, Melo MB, Cossette B, Kumar V, Patel NB, Tokatlian T, Menis S, Kulp DW, Burton DR, Murrell B, Schief WR, Bosinger SE, Ward AB, Watson CT, Silvestri G, Irvine DJ, Crotty S. Cirelli KM, et al. Among authors: melo mb. Cell. 2019 May 16;177(5):1153-1171.e28. doi: 10.1016/j.cell.2019.04.012. Epub 2019 May 9. Cell. 2019. PMID: 31080066 Free PMC article.
Engineered immunogen binding to alum adjuvant enhances humoral immunity.
Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, Agarwal Y, Li N, Burton DR, Ward AB, Schief WR, Crotty S, Irvine DJ. Moyer TJ, et al. Among authors: melo mb. Nat Med. 2020 Mar;26(3):430-440. doi: 10.1038/s41591-020-0753-3. Epub 2020 Feb 17. Nat Med. 2020. PMID: 32066977 Free PMC article.
158 results