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Antidrug antibodies against the polyethylene glycol moiety inhibit the procoagulant activity of therapeutic polyethylene glycolated factor VIII.
Pezeshkpoor B, Sereda N, Berkemeier AC, Matuschek I, Schwarz N, Turecek PL, Horneff S, Klein C, Goldmann G, Marquardt N, Albert T, Müller J, Oldenburg J. Pezeshkpoor B, et al. Among authors: berkemeier ac. J Thromb Haemost. 2023 Jun;21(6):1503-1514. doi: 10.1016/j.jtha.2023.03.011. Epub 2023 Mar 18. J Thromb Haemost. 2023. PMID: 36934798
Variants in FIX propeptide associated with vitamin K antagonist hypersensitivity: functional analysis and additional data confirming the common founder mutations.
Pezeshkpoor B, Czogalla KJ, Caspers M, Berkemeier AC, Liphardt K, Ghosh S, Kellner M, Ulrich S, Pavlova A, Oldenburg J. Pezeshkpoor B, et al. Among authors: berkemeier ac. Ann Hematol. 2018 Jun;97(6):1061-1069. doi: 10.1007/s00277-018-3264-2. Epub 2018 Feb 15. Ann Hematol. 2018. PMID: 29450643