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Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
Dmello C, Zhao J, Chen L, Gould A, Castro B, Arrieta VA, Zhang DY, Kim KS, Kanojia D, Zhang P, Miska J, Yeeravalli R, Habashy K, Saganty R, Kang SJ, Fares J, Liu C, Dunn G, Bartom E, Schipma MJ, Hsu PD, Alghamri MS, Lesniak MS, Heimberger AB, Rabadan R, Lee-Chang C, Sonabend AM. Dmello C, et al. Among authors: castro b. Nat Commun. 2023 Mar 22;14(1):1566. doi: 10.1038/s41467-023-36878-2. Nat Commun. 2023. PMID: 36949040 Free PMC article.
Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma.
Miska J, Rashidi A, Lee-Chang C, Gao P, Lopez-Rosas A, Zhang P, Burga R, Castro B, Xiao T, Han Y, Hou D, Sampat S, Cordero A, Stoolman JS, Horbinski CM, Burns M, Reshetnyak YK, Chandel NS, Lesniak MS. Miska J, et al. Among authors: castro b. Sci Adv. 2021 Feb 17;7(8):eabc8929. doi: 10.1126/sciadv.abc8929. Print 2021 Feb. Sci Adv. 2021. PMID: 33597238 Free PMC article.
The Interplay between Glioblastoma and Its Microenvironment.
Dapash M, Hou D, Castro B, Lee-Chang C, Lesniak MS. Dapash M, et al. Among authors: castro b. Cells. 2021 Aug 31;10(9):2257. doi: 10.3390/cells10092257. Cells. 2021. PMID: 34571905 Free PMC article. Review.
Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer.
Cordero A, Ramsey MD, Kanojia D, Fares J, Petrosyan E, Schwartz CW, Burga R, Zhang P, Rashidi A, Castro B, Xiao T, Lee-Chang C, Miska J, Balyasnikova IV, Ahmed AU, Lesniak MS. Cordero A, et al. Among authors: castro b. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2112491119. doi: 10.1073/pnas.2112491119. Proc Natl Acad Sci U S A. 2022. PMID: 34969858 Free PMC article.
Translocon-associated Protein Subunit SSR3 Determines and Predicts Susceptibility to Paclitaxel in Breast Cancer and Glioblastoma.
Dmello C, Sonabend A, Arrieta VA, Zhang DY, Kanojia D, Chen L, Gould A, Zhang J, Kang SJ, Winter J, Horbinski C, Amidei C, Győrffy B, Cordero A, Chang CL, Castro B, Hsu P, Ahmed AU, Lesniak MS, Stupp R, Sonabend AM. Dmello C, et al. Among authors: castro b. Clin Cancer Res. 2022 Jul 15;28(14):3156-3169. doi: 10.1158/1078-0432.CCR-21-2563. Clin Cancer Res. 2022. PMID: 35552677 Free PMC article.
TIGIT and PD-1 Immune Checkpoint Pathways Are Associated With Patient Outcome and Anti-Tumor Immunity in Glioblastoma.
Raphael I, Kumar R, McCarl LH, Shoger K, Wang L, Sandlesh P, Sneiderman CT, Allen J, Zhai S, Campagna ML, Foster A, Bruno TC, Agnihotri S, Hu B, Castro BA, Lieberman FS, Broniscer A, Diaz AA, Amankulor NM, Rajasundaram D, Pollack IF, Kohanbash G. Raphael I, et al. Among authors: castro ba. Front Immunol. 2021 May 7;12:637146. doi: 10.3389/fimmu.2021.637146. eCollection 2021. Front Immunol. 2021. PMID: 34025646 Free PMC article.
Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
Johnson M, Bell A, Lauing KL, Ladomersky E, Zhai L, Penco-Campillo M, Shah Y, Mauer E, Xiu J, Nicolaides T, Drumm M, McCortney K, Elemento O, Kim M, Bommi P, Low JT, Memon R, Wu J, Zhao J, Mi X, Glantz MJ, Sengupta S, Castro B, Yamini B, Horbinski C, Baker DJ, Walunas TL, Schiltz GE, Lukas RV, Wainwright DA. Johnson M, et al. Among authors: castro b. Clin Cancer Res. 2023 Dec 1;29(23):4973-4989. doi: 10.1158/1078-0432.CCR-23-0834. Clin Cancer Res. 2023. PMID: 37725593 Free PMC article.
Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma.
Shih DJH, Nayyar N, Bihun I, Dagogo-Jack I, Gill CM, Aquilanti E, Bertalan M, Kaplan A, D'Andrea MR, Chukwueke U, Ippen FM, Alvarez-Breckenridge C, Camarda ND, Lastrapes M, McCabe D, Kuter B, Kaufman B, Strickland MR, Martinez-Gutierrez JC, Nagabhushan D, De Sauvage M, White MD, Castro BA, Hoang K, Kaneb A, Batchelor ED, Paek SH, Park SH, Martinez-Lage M, Berghoff AS, Merrill P, Gerstner ER, Batchelor TT, Frosch MP, Frazier RP, Borger DR, Iafrate AJ, Johnson BE, Santagata S, Preusser M, Cahill DP, Carter SL, Brastianos PK. Shih DJH, et al. Among authors: castro ba. Nat Genet. 2020 Apr;52(4):371-377. doi: 10.1038/s41588-020-0592-7. Epub 2020 Mar 23. Nat Genet. 2020. PMID: 32203465 Free PMC article.
699 results