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Checkpoint kinase 1/2 inhibition potentiates anti-tumoral immune response and sensitizes gliomas to immune checkpoint blockade.
Dmello C, Zhao J, Chen L, Gould A, Castro B, Arrieta VA, Zhang DY, Kim KS, Kanojia D, Zhang P, Miska J, Yeeravalli R, Habashy K, Saganty R, Kang SJ, Fares J, Liu C, Dunn G, Bartom E, Schipma MJ, Hsu PD, Alghamri MS, Lesniak MS, Heimberger AB, Rabadan R, Lee-Chang C, Sonabend AM. Dmello C, et al. Among authors: heimberger ab. Nat Commun. 2023 Mar 22;14(1):1566. doi: 10.1038/s41467-023-36878-2. Nat Commun. 2023. PMID: 36949040 Free PMC article.
CD8+ T-cell-Mediated Immunoediting Influences Genomic Evolution and Immune Evasion in Murine Gliomas.
Kane JR, Zhao J, Tsujiuchi T, Laffleur B, Arrieta VA, Mahajan A, Rao G, Mela A, Dmello C, Chen L, Zhang DY, González-Buendia E, Lee-Chang C, Xiao T, Rothschild G, Basu U, Horbinski C, Lesniak MS, Heimberger AB, Rabadan R, Canoll P, Sonabend AM. Kane JR, et al. Among authors: heimberger ab. Clin Cancer Res. 2020 Aug 15;26(16):4390-4401. doi: 10.1158/1078-0432.CCR-19-3104. Epub 2020 May 19. Clin Cancer Res. 2020. PMID: 32430477 Free PMC article.
Anti-PD-1 Induces M1 Polarization in the Glioma Microenvironment and Exerts Therapeutic Efficacy in the Absence of CD8 Cytotoxic T Cells.
Rao G, Latha K, Ott M, Sabbagh A, Marisetty A, Ling X, Zamler D, Doucette TA, Yang Y, Kong LY, Wei J, Fuller GN, Benavides F, Sonabend AM, Long J, Li S, Curran M, Heimberger AB. Rao G, et al. Among authors: heimberger ab. Clin Cancer Res. 2020 Sep 1;26(17):4699-4712. doi: 10.1158/1078-0432.CCR-19-4110. Epub 2020 Jun 18. Clin Cancer Res. 2020. PMID: 32554515 Free PMC article.
Circadian regulation of cancer cell and tumor microenvironment crosstalk.
Xuan W, Khan F, James CD, Heimberger AB, Lesniak MS, Chen P. Xuan W, et al. Among authors: heimberger ab. Trends Cell Biol. 2021 Nov;31(11):940-950. doi: 10.1016/j.tcb.2021.06.008. Epub 2021 Jul 13. Trends Cell Biol. 2021. PMID: 34272133 Free PMC article. Review.
New Approaches to Glioblastoma.
Khasraw M, Fujita Y, Lee-Chang C, Balyasnikova IV, Najem H, Heimberger AB. Khasraw M, et al. Among authors: heimberger ab. Annu Rev Med. 2022 Jan 27;73:279-292. doi: 10.1146/annurev-med-042420-102102. Epub 2021 Oct 19. Annu Rev Med. 2022. PMID: 34665646 Free PMC article. Review.
CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease.
Najem H, Marisetty A, Horbinski C, Long J, Huse JT, Glitza Oliva IC, Ferguson SD, Kumthekar PU, Wainwright DA, Chen P, Lesniak MS, Burks JK, Heimberger AB. Najem H, et al. Among authors: heimberger ab. Front Immunol. 2021 Oct 8;12:745893. doi: 10.3389/fimmu.2021.745893. eCollection 2021. Front Immunol. 2021. PMID: 34691054 Free PMC article.
Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.
McGrail DJ, Pilié PG, Dai H, Lam TNA, Liang Y, Voorwerk L, Kok M, Zhang XH, Rosen JM, Heimberger AB, Peterson CB, Jonasch E, Lin SY. McGrail DJ, et al. Among authors: heimberger ab. Sci Transl Med. 2021 Oct 27;13(617):eabe6201. doi: 10.1126/scitranslmed.abe6201. Epub 2021 Oct 27. Sci Transl Med. 2021. PMID: 34705519 Free PMC article.
The Eclectic Nature of Glioma-Infiltrating Macrophages and Microglia.
Arrieta VA, Najem H, Petrosyan E, Lee-Chang C, Chen P, Sonabend AM, Heimberger AB. Arrieta VA, et al. Among authors: heimberger ab. Int J Mol Sci. 2021 Dec 13;22(24):13382. doi: 10.3390/ijms222413382. Int J Mol Sci. 2021. PMID: 34948178 Free PMC article. Review.
235 results