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Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA ubiquitination.
Cell Rep. 2023 Apr 25;42(4):112296. doi: 10.1016/j.celrep.2023.112296. Epub 2023 Mar 23.
Cell Rep. 2023.
PMID: 36961817
Free PMC article.
Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination.
Wang YC, Kelso AA, Karamafrooz A, Chen YH, Chen WK, Cheng CT, Qi Y, Gu L, Malkas L, Kung HJ, Moldovan GL, Ciccia A, Stark JM, Ann DK.
Wang YC, et al. Among authors: karamafrooz a.
bioRxiv [Preprint]. 2023 Feb 3:2023.01.31.526362. doi: 10.1101/2023.01.31.526362.
bioRxiv. 2023.
PMID: 36778247
Free PMC article.
Updated.
Preprint.
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Integrated Phosphoproteomics for Identifying Substrates of Human Protein Kinase A (PRKACA) and Its Oncogenic Mutant DNAJB1-PRKACA.
Karamafrooz A, Brennan J, Thomas DD, Parker LL.
Karamafrooz A, et al.
J Proteome Res. 2021 Oct 1;20(10):4815-4830. doi: 10.1021/acs.jproteome.1c00500. Epub 2021 Aug 26.
J Proteome Res. 2021.
PMID: 34436901
Free PMC article.
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Author Correction: Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A.
Olivieri C, Walker C, Karamafrooz A, Wang Y, Manu VS, Porcelli F, Blumenthal DK, Thomas DD, Bernlohr DA, Simon SM, Taylor SS, Veglia G.
Olivieri C, et al. Among authors: karamafrooz a.
Commun Biol. 2021 Apr 6;4(1):446. doi: 10.1038/s42003-021-02006-3.
Commun Biol. 2021.
PMID: 33824409
Free PMC article.
No abstract available.
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Defective internal allosteric network imparts dysfunctional ATP/substrate-binding cooperativity in oncogenic chimera of protein kinase A.
Olivieri C, Walker C, Karamafrooz A, Wang Y, Manu VS, Porcelli F, Blumenthal DK, Thomas DD, Bernlohr DA, Simon SM, Taylor SS, Veglia G.
Olivieri C, et al. Among authors: karamafrooz a.
Commun Biol. 2021 Mar 10;4(1):321. doi: 10.1038/s42003-021-01819-6.
Commun Biol. 2021.
PMID: 33692454
Free PMC article.
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Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity.
Walker C, Wang Y, Olivieri C, Karamafrooz A, Casby J, Bathon K, Calebiro D, Gao J, Bernlohr DA, Taylor SS, Veglia G.
Walker C, et al. Among authors: karamafrooz a.
Sci Adv. 2019 Aug 28;5(8):eaaw9298. doi: 10.1126/sciadv.aaw9298. eCollection 2019 Aug.
Sci Adv. 2019.
PMID: 31489371
Free PMC article.
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Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma.
Tomasini MD, Wang Y, Karamafrooz A, Li G, Beuming T, Gao J, Taylor SS, Veglia G, Simon SM.
Tomasini MD, et al. Among authors: karamafrooz a.
Sci Rep. 2018 Jan 15;8(1):720. doi: 10.1038/s41598-017-18956-w.
Sci Rep. 2018.
PMID: 29335433
Free PMC article.
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