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Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo.
Richmond JM, Strassner JP, Zapata L Jr, Garg M, Riding RL, Refat MA, Fan X, Azzolino V, Tovar-Garza A, Tsurushita N, Pandya AG, Tso JY, Harris JE. Richmond JM, et al. Among authors: tsurushita n. Sci Transl Med. 2018 Jul 18;10(450):eaam7710. doi: 10.1126/scitranslmed.aam7710. Sci Transl Med. 2018. PMID: 30021889 Free PMC article.
CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma.
Hsi ED, Steinle R, Balasa B, Szmania S, Draksharapu A, Shum BP, Huseni M, Powers D, Nanisetti A, Zhang Y, Rice AG, van Abbema A, Wong M, Liu G, Zhan F, Dillon M, Chen S, Rhodes S, Fuh F, Tsurushita N, Kumar S, Vexler V, Shaughnessy JD Jr, Barlogie B, van Rhee F, Hussein M, Afar DE, Williams MB. Hsi ED, et al. Among authors: tsurushita n. Clin Cancer Res. 2008 May 1;14(9):2775-84. doi: 10.1158/1078-0432.CCR-07-4246. Clin Cancer Res. 2008. PMID: 18451245 Free PMC article.
An engineered human IgG1 antibody with longer serum half-life.
Hinton PR, Xiong JM, Johlfs MG, Tang MT, Keller S, Tsurushita N. Hinton PR, et al. Among authors: tsurushita n. J Immunol. 2006 Jan 1;176(1):346-56. doi: 10.4049/jimmunol.176.1.346. J Immunol. 2006. PMID: 16365427
Amphiregulin and epidermal hyperplasia: amphiregulin is required to maintain the psoriatic phenotype of human skin grafts on severe combined immunodeficient mice.
Bhagavathula N, Nerusu KC, Fisher GJ, Liu G, Thakur AB, Gemmell L, Kumar S, Xu ZH, Hinton P, Tsurushita N, Landolfi NF, Voorhees JJ, Varani J. Bhagavathula N, et al. Among authors: tsurushita n. Am J Pathol. 2005 Apr;166(4):1009-16. doi: 10.1016/S0002-9440(10)62322-X. Am J Pathol. 2005. PMID: 15793282 Free PMC article.
Humanization of a chicken anti-IL-12 monoclonal antibody.
Tsurushita N, Park M, Pakabunto K, Ong K, Avdalovic A, Fu H, Jia A, Vásquez M, Kumar S. Tsurushita N, et al. J Immunol Methods. 2004 Dec;295(1-2):9-19. doi: 10.1016/j.jim.2004.08.018. J Immunol Methods. 2004. PMID: 15627607
31 results