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ATM inhibition enhances the efficacy of radiation across distinct molecular subgroups of pediatric high-grade glioma.
Xie J, Kuriakose T, Bianski B, Twarog N, Savage E, Xu K, Zhu X, He C, Hansen B, Wang H, High A, Li Y, Rehg JE, Tillman HS, Freeman BB, Rankovic Z, Onar-Thomas A, Fan Y, Wu G, Peng J, Miller S, Baker SJ, Shelat AA, Tinkle CL. Xie J, et al. Neuro Oncol. 2023 Oct 3;25(10):1828-1841. doi: 10.1093/neuonc/noad064. Neuro Oncol. 2023. PMID: 36971093 Free PMC article.
A phase-1 pharmacokinetic optimal dosing study of intraventricular topotecan for children with neoplastic meningitis: a Pediatric Brain Tumor Consortium study.
Blaney SM, Tagen M, Onar-Thomas A, Berg SL, Gururangan S, Scorsone K, Su J, Goldman S, Kieran MW, Kun L, Boyett J, Stewart C. Blaney SM, et al. Pediatr Blood Cancer. 2013 Apr;60(4):627-32. doi: 10.1002/pbc.24309. Epub 2012 Sep 21. Pediatr Blood Cancer. 2013. PMID: 23002039 Free PMC article. Clinical Trial.
Phase I trial of weekly MK-0752 in children with refractory central nervous system malignancies: a pediatric brain tumor consortium study.
Hoffman LM, Fouladi M, Olson J, Daryani VM, Stewart CF, Wetmore C, Kocak M, Onar-Thomas A, Wagner L, Gururangan S, Packer RJ, Blaney SM, Gajjar A, Kun LE, Boyett JM, Gilbertson RJ. Hoffman LM, et al. Childs Nerv Syst. 2015 Aug;31(8):1283-9. doi: 10.1007/s00381-015-2725-3. Epub 2015 May 1. Childs Nerv Syst. 2015. PMID: 25930724 Free PMC article. Clinical Trial.
A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors.
Kieran MW, Chi S, Goldman S, Onar-Thomas A, Poussaint TY, Vajapeyam S, Fahey F, Wu S, Turner DC, Stewart CF, Moses M, Packer RJ, Jakacki R, Banerjee A, Boyett JM, Fouladi M, Kun L. Kieran MW, et al. Childs Nerv Syst. 2015 Sep;31(9):1433-45. doi: 10.1007/s00381-015-2812-5. Epub 2015 Jul 19. Childs Nerv Syst. 2015. PMID: 26188774 Free PMC article. Clinical Trial.
Regulatory T cell subsets in patients with medulloblastoma at diagnosis and during standard irradiation and chemotherapy (PBTC N-11).
Gururangan S, Reap E, Schmittling R, Kocak M, Reynolds R, Grant G, Onar-Thomas A, Baxter P, Pollack IF, Phillips P, Boyett J, Fouladi M, Mitchell D. Gururangan S, et al. Cancer Immunol Immunother. 2017 Dec;66(12):1589-1595. doi: 10.1007/s00262-017-2051-6. Epub 2017 Aug 20. Cancer Immunol Immunother. 2017. PMID: 28825123 Free PMC article.
118 results