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Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation.
Zhu Y, Ackers-Johnson M, Shanmugam MK, Pakkiri LS, Drum CL, Chen Y, Kim J, Paltzer WG, Mahmoud AI, Tan WLW, Lee MCJ, Jiang J, Luu DAT, Ng SL, Li PYQ, Wang A, Qi R, Ong GJX, Ng TY, Haigh JJ, Tiang Z, Richards AM, Foo RSY. Zhu Y, et al. Among authors: haigh jj. Circulation. 2024 Jun 4;149(23):1833-1851. doi: 10.1161/CIRCULATIONAHA.123.063965. Epub 2024 Apr 8. Circulation. 2024. PMID: 38586957
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
Conway JRW, Warren SC, Lee YK, McCulloch AT, Magenau A, Lee V, Metcalf XL, Stoehr J, Haigh K, Abdulkhalek L, Guaman CS, Reed DA, Murphy KJ, Pereira BA, Mélénec P, Chambers C, Latham SL, Lenthall H, Deenick EK, Ma Y, Phan T, Lim E, Joshua AM, Walters S, Grey ST, Shi YC, Zhang L, Herzog H, Croucher DR, Philp A, Scheele CLGJ, Herrmann D, Sansom OJ, Morton JP, Papa A, Haigh JJ, Nobis M, Timpson P. Conway JRW, et al. Among authors: haigh jj. Sci Adv. 2023 Apr 28;9(17):eadf9063. doi: 10.1126/sciadv.adf9063. Epub 2023 Apr 26. Sci Adv. 2023. PMID: 37126544 Free PMC article.
MEF2C opposes Notch in lymphoid lineage decision and drives leukemia in the thymus.
Canté-Barrett K, Meijer MT, Cordo' V, Hagelaar R, Yang W, Yu J, Smits WK, Nulle ME, Jansen JP, Pieters R, Yang JJ, Haigh JJ, Goossens S, Meijerink JP. Canté-Barrett K, et al. Among authors: haigh jj. JCI Insight. 2022 Jul 8;7(13):e150363. doi: 10.1172/jci.insight.150363. JCI Insight. 2022. PMID: 35536646 Free PMC article.
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.
Wang J, Farkas C, Benyoucef A, Carmichael C, Haigh K, Wong N, Huylebroeck D, Stemmler MP, Brabletz S, Brabletz T, Nefzger CM, Goossens S, Berx G, Polo JM, Haigh JJ. Wang J, et al. Among authors: haigh jj. PLoS Biol. 2021 Sep 22;19(9):e3001394. doi: 10.1371/journal.pbio.3001394. eCollection 2021 Sep. PLoS Biol. 2021. PMID: 34550965 Free PMC article.
83 results