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Safeguarding CRISPR-Cas9 gene drives in yeast.
DiCarlo JE, Chavez A, Dietz SL, Esvelt KM, Church GM. DiCarlo JE, et al. Among authors: chavez a. Nat Biotechnol. 2015 Dec;33(12):1250-1255. doi: 10.1038/nbt.3412. Epub 2015 Nov 16. Nat Biotechnol. 2015. PMID: 26571100 Free PMC article.
Comparison of Cas9 activators in multiple species.
Chavez A, Tuttle M, Pruitt BW, Ewen-Campen B, Chari R, Ter-Ovanesyan D, Haque SJ, Cecchi RJ, Kowal EJK, Buchthal J, Housden BE, Perrimon N, Collins JJ, Church G. Chavez A, et al. Nat Methods. 2016 Jul;13(7):563-567. doi: 10.1038/nmeth.3871. Epub 2016 May 23. Nat Methods. 2016. PMID: 27214048 Free PMC article.
An enhanced CRISPR repressor for targeted mammalian gene regulation.
Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM. Yeo NC, et al. Among authors: chavez a. Nat Methods. 2018 Aug;15(8):611-616. doi: 10.1038/s41592-018-0048-5. Epub 2018 Jul 16. Nat Methods. 2018. PMID: 30013045 Free PMC article.
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference.
Xiong K, Marquart KF, la Cour Karottki KJ, Li S, Shamie I, Lee JS, Gerling S, Yeo NC, Chavez A, Lee GM, Lewis NE, Kildegaard HF. Xiong K, et al. Among authors: chavez a. Biotechnol Bioeng. 2019 Jul;116(7):1813-1819. doi: 10.1002/bit.26969. Epub 2019 Apr 2. Biotechnol Bioeng. 2019. PMID: 30883679 Free PMC article.
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir.
Iketani S, Mohri H, Culbertson B, Hong SJ, Duan Y, Luck MI, Annavajhala MK, Guo Y, Sheng Z, Uhlemann AC, Goff SP, Sabo Y, Yang H, Chavez A, Ho DD. Iketani S, et al. Among authors: chavez a. Nature. 2023 Jan;613(7944):558-564. doi: 10.1038/s41586-022-05514-2. Epub 2022 Nov 9. Nature. 2023. PMID: 36351451 Free PMC article.
Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir.
Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, Bian Q, Wang H, Sun H, Hong SJ, Culbertson B, Mohri H, Luck MI, Zhu Y, Liu X, Lu Y, Yang X, Yang K, Sabo Y, Chavez A, Goff SP, Rao Z, Ho DD, Yang H. Duan Y, et al. Among authors: chavez a. Nature. 2023 Oct;622(7982):376-382. doi: 10.1038/s41586-023-06609-0. Epub 2023 Sep 11. Nature. 2023. PMID: 37696289
556 results