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A randomized, controlled Phase 1b trial of the Sm-TSP-2 Vaccine for intestinal schistosomiasis in healthy Brazilian adults living in an endemic area.
Diemert DJ, Correa-Oliveira R, Fraga CG, Talles F, Silva MR, Patel SM, Galbiati S, Kennedy JK, Lundeen JS, Gazzinelli MF, Li G, Hoeweler L, Deye GA, Bottazzi ME, Hotez PJ, El Sahly HM, Keitel WA, Bethony J, Atmar RL. Diemert DJ, et al. Among authors: li g. PLoS Negl Trop Dis. 2023 Mar 30;17(3):e0011236. doi: 10.1371/journal.pntd.0011236. eCollection 2023 Mar. PLoS Negl Trop Dis. 2023. PMID: 36996185 Free PMC article. Clinical Trial.
Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine.
Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Brelsford JB, et al. Among authors: li g. PLoS Negl Trop Dis. 2017 Feb 13;11(2):e0005385. doi: 10.1371/journal.pntd.0005385. eCollection 2017 Feb. PLoS Negl Trop Dis. 2017. PMID: 28192438 Free PMC article.
Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults.
Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, Li G, Peng J, Correa-Oliveira R, Hotez P, Bethony J. Diemert DJ, et al. Among authors: li g. PLoS Negl Trop Dis. 2017 May 2;11(5):e0005574. doi: 10.1371/journal.pntd.0005574. eCollection 2017 May. PLoS Negl Trop Dis. 2017. PMID: 28464026 Free PMC article. Clinical Trial.
Controlled Human Hookworm Infection: Accelerating Human Hookworm Vaccine Development.
Diemert D, Campbell D, Brelsford J, Leasure C, Li G, Peng J, Zumer M, Younes N, Bottazzi ME, Mejia R, Pritchard DI, Hawdon JM, Bethony JM. Diemert D, et al. Among authors: li g. Open Forum Infect Dis. 2018 Apr 19;5(5):ofy083. doi: 10.1093/ofid/ofy083. eCollection 2018 May. Open Forum Infect Dis. 2018. PMID: 29780848 Free PMC article.
Correction: Safety and immunogenicity of the Na-GST-1 hookworm vaccine in Brazilian and American adults.
Diemert DJ, Freire J, Valente V, Fraga CG, Talles F, Grahek S, Campbell D, Jariwala A, Periago MV, Enk M, Gazzinelli MF, Bottazzi ME, Hamilton R, Brelsford J, Yakovleva A, Li G, Peng J, Correa-Oliveira R, Hotez P, Bethony J. Diemert DJ, et al. Among authors: li g. PLoS Negl Trop Dis. 2020 Aug 17;14(8):e0008670. doi: 10.1371/journal.pntd.0008670. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32804987 Free PMC article.
Safety and immunogenicity of co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in Gabonese adults: a randomised, controlled, double-blind, phase 1 dose-escalation trial.
Adegnika AA, de Vries SG, Zinsou FJ, Honkepehedji YJ, Dejon Agobé JC, Vodonou KG, Bikangui R, Bouyoukou Hounkpatin A, Bache EB, Massinga Loembe M, van Leeuwen R, Molemans M, Kremsner PG, Yazdanbakhsh M, Hotez PJ, Bottazzi ME, Li G, Bethony JM, Diemert DJ, Grobusch MP; HookVac Consortium. Adegnika AA, et al. Among authors: li g. Lancet Infect Dis. 2021 Feb;21(2):275-285. doi: 10.1016/S1473-3099(20)30288-7. Epub 2020 Sep 11. Lancet Infect Dis. 2021. PMID: 32926834 Clinical Trial.
Safety and immunogenicity of the co-administered Na-APR-1 and Na-GST-1 hookworm vaccines in school-aged children in Gabon: a randomised, controlled, observer-blind, phase 1, dose-escalation trial.
Zinsou JF, Diemert DJ, Dejon-Agobé JC, Adégbité BR, Honkpehedji YJ, Vodonou KG, Bikangui R, Edoa JR, Massinga Loembe M, Li G, Yazdanbakhsh M, Bottazzi ME, van Leeuwen R, Kremsner PG, Hotez PJ, Bethony JM, Grobusch MP, Adegnika AA. Zinsou JF, et al. Among authors: li g. Lancet Infect Dis. 2024 Mar 18:S1473-3099(24)00104-X. doi: 10.1016/S1473-3099(24)00104-X. Online ahead of print. Lancet Infect Dis. 2024. PMID: 38513684
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