Avezov E - Search Results

1

Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.

Mukadam AS, Miller LVC, Smith AE, Vaysburd M, Sakya SA, Sanford S, Keeling S, Tuck BJ, Katsinelos T, Green C, Skov L, Kaalund SS, Foss S, Mayes K, O'Connell K, Wing M, Knox C, Banbury J, Avezov E, Rowe JB, Goedert M, Andersen JT, James LC, McEwan WA. Mukadam AS, et al. Among authors: avezov e. Science. 2023 Mar 31;379(6639):1336-1341. doi: 10.1126/science.abn1366. Epub 2023 Mar 30. Science. 2023. PMID: 36996217 Free PMC article.

2

Stress-induced protein disaggregation in the endoplasmic reticulum catalysed by BiP.

Melo EP, Konno T, Farace I, Awadelkareem MA, Skov LR, Teodoro F, Sancho TP, Paton AW, Paton JC, Fares M, Paulo PMR, Zhang X, Avezov E. Melo EP, et al. Among authors: avezov e. Nat Commun. 2022 May 6;13(1):2501. doi: 10.1038/s41467-022-30238-2. Nat Commun. 2022. PMID: 35523806 Free PMC article.

3

The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes.

Lu M, van Tartwijk FW, Lin JQ, Nijenhuis W, Parutto P, Fantham M, Christensen CN, Avezov E, Holt CE, Tunnacliffe A, Holcman D, Kapitein L, Schierle GSK, Kaminski CF. Lu M, et al. Among authors: avezov e. Sci Adv. 2020 Dec 16;6(51):eabc7209. doi: 10.1126/sciadv.abc7209. Print 2020 Dec. Sci Adv. 2020. PMID: 33328230 Free PMC article.

4

Intracellular Aβ42 Aggregation Leads to Cellular Thermogenesis.

Chung CW, Stephens AD, Konno T, Ward E, Avezov E, Kaminski CF, Hassanali AA, Kaminski Schierle GS. Chung CW, et al. Among authors: avezov e. J Am Chem Soc. 2022 Jun 8;144(22):10034-10041. doi: 10.1021/jacs.2c03599. Epub 2022 May 26. J Am Chem Soc. 2022. PMID: 35616634 Free PMC article.

5

Intracellular Sources of ROS/H₂O₂ in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum.

Konno T, Melo EP, Chambers JE, Avezov E. Konno T, et al. Among authors: avezov e. Cells. 2021 Jan 25;10(2):233. doi: 10.3390/cells10020233. Cells. 2021. PMID: 33504070 Free PMC article. Review.

6

Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm.

Gulati P, Avezov E, Ma M, Antrobus R, Lehner P, O'Rahilly S, Yeo GS. Gulati P, et al. Among authors: avezov e. Biosci Rep. 2014 Oct 22;34(5):e00144. doi: 10.1042/BSR20140111. Biosci Rep. 2014. PMID: 25242086 Free PMC article.

7

Z-α₁-antitrypsin polymers impose molecular filtration in the endoplasmic reticulum after undergoing phase transition to a solid state.

Chambers JE, Zubkov N, Kubánková M, Nixon-Abell J, Mela I, Abreu S, Schwiening M, Lavarda G, López-Duarte I, Dickens JA, Torres T, Kaminski CF, Holt LJ, Avezov E, Huntington JA, George-Hyslop PS, Kuimova MK, Marciniak SJ. Chambers JE, et al. Among authors: avezov e. Sci Adv. 2022 Apr 8;8(14):eabm2094. doi: 10.1126/sciadv.abm2094. Epub 2022 Apr 8. Sci Adv. 2022. PMID: 35394846 Free PMC article.

8

An Optical Technique for Mapping Microviscosity Dynamics in Cellular Organelles.

Chambers JE, Kubánková M, Huber RG, López-Duarte I, Avezov E, Bond PJ, Marciniak SJ, Kuimova MK. Chambers JE, et al. Among authors: avezov e. ACS Nano. 2018 May 22;12(5):4398-4407. doi: 10.1021/acsnano.8b00177. Epub 2018 Apr 18. ACS Nano. 2018. PMID: 29648785 Free article.

9

High-throughput super-resolution single-particle trajectory analysis reconstructs organelle dynamics and membrane reorganization.

Parutto P, Heck J, Lu M, Kaminski C, Avezov E, Heine M, Holcman D. Parutto P, et al. Among authors: avezov e. Cell Rep Methods. 2022 Aug 22;2(8):100277. doi: 10.1016/j.crmeth.2022.100277. eCollection 2022 Aug 22. Cell Rep Methods. 2022. PMID: 36046627 Free PMC article.

10

ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity.

Mehmeti I, Lortz S, Avezov E, Jörns A, Lenzen S. Mehmeti I, et al. Among authors: avezov e. Free Radic Biol Med. 2017 Nov;112:121-130. doi: 10.1016/j.freeradbiomed.2017.07.021. Epub 2017 Jul 24. Free Radic Biol Med. 2017. PMID: 28751022

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