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Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.
Mukadam AS, Miller LVC, Smith AE, Vaysburd M, Sakya SA, Sanford S, Keeling S, Tuck BJ, Katsinelos T, Green C, Skov L, Kaalund SS, Foss S, Mayes K, O'Connell K, Wing M, Knox C, Banbury J, Avezov E, Rowe JB, Goedert M, Andersen JT, James LC, McEwan WA. Mukadam AS, et al. Among authors: vaysburd m. Science. 2023 Mar 31;379(6639):1336-1341. doi: 10.1126/science.abn1366. Epub 2023 Mar 30. Science. 2023. PMID: 36996217 Free PMC article.
Intracellular antibody receptor TRIM21 prevents fatal viral infection.
Vaysburd M, Watkinson RE, Cooper H, Reed M, O'Connell K, Smith J, Cruickshanks J, James LC. Vaysburd M, et al. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12397-401. doi: 10.1073/pnas.1301918110. Epub 2013 Jul 9. Proc Natl Acad Sci U S A. 2013. PMID: 23840060 Free PMC article.
Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation.
McEwan WA, Falcon B, Vaysburd M, Clift D, Oblak AL, Ghetti B, Goedert M, James LC. McEwan WA, et al. Among authors: vaysburd m. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):574-579. doi: 10.1073/pnas.1607215114. Epub 2017 Jan 3. Proc Natl Acad Sci U S A. 2017. PMID: 28049840 Free PMC article.
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination.
Bottermann M, Foss S, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Hirst JC, McAdam MB, Slodkowicz G, Hutchinson E, Kozik P, Andersen JT, James LC. Bottermann M, et al. Among authors: vaysburd m. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10440-10445. doi: 10.1073/pnas.1806314115. Epub 2018 Sep 12. Proc Natl Acad Sci U S A. 2018. PMID: 30209217 Free PMC article.
Complement C4 Prevents Viral Infection through Capsid Inactivation.
Bottermann M, Foss S, Caddy SL, Clift D, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Lode HE, McAdam MB, Sandlie I, Andersen JT, James LC. Bottermann M, et al. Among authors: vaysburd m. Cell Host Microbe. 2019 Apr 10;25(4):617-629.e7. doi: 10.1016/j.chom.2019.02.016. Epub 2019 Mar 26. Cell Host Microbe. 2019. PMID: 30926239 Free PMC article.
31 results