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Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication.
Hinterberger M, Endt K, Bathke B, Habjan M, Heiseke A, Schweneker M, Von Rohrscheidt J, Atay C, Chaplin P, Kalla M, Hausmann J, Schmittwolf C, Lauterbach H, Volkmann A, Hochrein H, Medina-Echeverz J. Hinterberger M, et al. Among authors: chaplin p. Sci Rep. 2023 Mar 30;13(1):5162. doi: 10.1038/s41598-023-32060-2. Sci Rep. 2023. PMID: 36997583 Free PMC article.
One- and Two-Dose Vaccinations With Modified Vaccinia Ankara-Bavarian Nordic Induce Durable B-Cell Memory Responses Comparable to Replicating Smallpox Vaccines.
Ilchmann H, Samy N, Reichhardt D, Schmidt D, Powell JD, Meyer TPH, Silbernagl G, Nichols R, Weidenthaler H, De Moerlooze L, Chen L, Chaplin P. Ilchmann H, et al. Among authors: chaplin p. J Infect Dis. 2023 May 12;227(10):1203-1213. doi: 10.1093/infdis/jiac455. J Infect Dis. 2023. PMID: 36408618 Free PMC article. Clinical Trial.
A Capsid Virus-Like Particle-Based SARS-CoV-2 Vaccine Induces High Levels of Antibodies and Protects Rhesus Macaques.
Volkmann A, Koopman G, Mooij P, Verschoor EJ, Verstrepen BE, Bogers WMJM, Idorn M, Paludan SR, Vang S, Nielsen MA, Sander AF, Schmittwolf C, Hochrein H, Chaplin P. Volkmann A, et al. Among authors: chaplin p. Front Immunol. 2022 Apr 5;13:857440. doi: 10.3389/fimmu.2022.857440. eCollection 2022. Front Immunol. 2022. PMID: 35479095 Free PMC article.
Human Antibody Responses Following Vaccinia Immunization Using Protein Microarrays and Correlation With Cell-Mediated Immunity and Antibody-Dependent Cellular Cytotoxicity Responses.
Frey SE, Stapleton JT, Ballas ZK, Rasmussen WL, Kaufman TM, Blevins TP, Jensen TL, Davies DH, Tary-Lehmann M, Chaplin P, Hill H, Goll JB; DMID 09-0002 MVA Vaccine Study Group. Frey SE, et al. Among authors: chaplin p. J Infect Dis. 2021 Oct 28;224(8):1372-1382. doi: 10.1093/infdis/jiab111. J Infect Dis. 2021. PMID: 33675226 Free PMC article. Clinical Trial.
Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory.
Hinterberger M, Giessel R, Fiore G, Graebnitz F, Bathke B, Wennier S, Chaplin P, Melero I, Suter M, Lauterbach H, Berraondo P, Hochrein H, Medina-Echeverz J. Hinterberger M, et al. Among authors: chaplin p. J Immunother Cancer. 2021 Feb;9(2):e001586. doi: 10.1136/jitc-2020-001586. J Immunother Cancer. 2021. PMID: 33579736 Free PMC article.
Broad Antibody and Cellular Immune Response From a Phase 2 Clinical Trial With a Novel Multivalent Poxvirus-Based Respiratory Syncytial Virus Vaccine.
Jordan E, Lawrence SJ, Meyer TPH, Schmidt D, Schultz S, Mueller J, Stroukova D, Koenen B, Gruenert R, Silbernagl G, Vidojkovic S, Chen LM, Weidenthaler H, Samy N, Chaplin P. Jordan E, et al. Among authors: chaplin p. J Infect Dis. 2021 Mar 29;223(6):1062-1072. doi: 10.1093/infdis/jiaa460. J Infect Dis. 2021. PMID: 32726422 Clinical Trial.
A Modified Vaccine against Smallpox. Reply.
Pittman PR, Weidenthaler H, Chaplin P. Pittman PR, et al. Among authors: chaplin p. N Engl J Med. 2020 Mar 26;382(13):1285-1286. doi: 10.1056/NEJMc2001156. N Engl J Med. 2020. PMID: 32212534 No abstract available.
77 results