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373 results

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Page 1
Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma.
Chen Z, Soni N, Pinero G, Giotti B, Eddins DJ, Lindblad KE, Ross JL, Puigdelloses Vallcorba M, Joshi T, Angione A, Thomason W, Keane A, Tsankova NM, Gutmann DH, Lira SA, Lujambio A, Ghosn EEB, Tsankov AM, Hambardzumyan D. Chen Z, et al. Among authors: ross jl. Nat Commun. 2023 Apr 3;14(1):1839. doi: 10.1038/s41467-023-37361-8. Nat Commun. 2023. PMID: 37012245 Free PMC article.
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.
Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG. Núñez FJ, et al. Among authors: ross jl. Sci Transl Med. 2019 Feb 13;11(479):eaaq1427. doi: 10.1126/scitranslmed.aaq1427. Sci Transl Med. 2019. PMID: 30760578 Free PMC article.
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors.
Kaffes I, Szulzewsky F, Chen Z, Herting CJ, Gabanic B, Velázquez Vega JE, Shelton J, Switchenko JM, Ross JL, McSwain LF, Huse JT, Westermark B, Nelander S, Forsberg-Nilsson K, Uhrbom L, Maturi NP, Cimino PJ, Holland EC, Kettenmann H, Brennan CW, Brat DJ, Hambardzumyan D. Kaffes I, et al. Among authors: ross jl. Oncoimmunology. 2019 Aug 22;8(11):e1655360. doi: 10.1080/2162402X.2019.1655360. eCollection 2019. Oncoimmunology. 2019. PMID: 31646100 Free PMC article.
Genetic driver mutations introduced in identical cell-of-origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade.
Chen Z, Herting CJ, Ross JL, Gabanic B, Puigdelloses Vallcorba M, Szulzewsky F, Wojciechowicz ML, Cimino PJ, Ezhilarasan R, Sulman EP, Ying M, Ma'ayan A, Read RD, Hambardzumyan D. Chen Z, et al. Among authors: ross jl. Glia. 2020 Oct;68(10):2148-2166. doi: 10.1002/glia.23883. Epub 2020 Jul 8. Glia. 2020. PMID: 32639068 Free PMC article.
Tumour immune landscape of paediatric high-grade gliomas.
Ross JL, Velazquez Vega J, Plant A, MacDonald TJ, Becher OJ, Hambardzumyan D. Ross JL, et al. Brain. 2021 Oct 22;144(9):2594-2609. doi: 10.1093/brain/awab155. Brain. 2021. PMID: 33856022 Free PMC article. Review.
YB1 modulates the DNA damage response in medulloblastoma.
McSwain LF, Pillsbury CE, Haji-Seyed-Javadi R, Rath SK, Chen V, Huang T, Shahab SW, Kunhiraman H, Ross J, Price GA, Dey A, Hambardzumyan D, MacDonald T, Yu DS, Porter CC, Kenney AM. McSwain LF, et al. Sci Rep. 2023 May 19;13(1):8087. doi: 10.1038/s41598-023-35220-6. Sci Rep. 2023. PMID: 37208357 Free PMC article.
Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
McSwain LF, Pillsbury CE, Haji-Seyed-Javadi R, Rath SK, Chen V, Huang T, Shahab SW, Kunhiraman H, Ross J, Price GA, Dey A, Hambardzumyan D, MacDonald T, Yu DS, Porter CC, Kenney AM. McSwain LF, et al. Sci Rep. 2023 Jun 15;13(1):9717. doi: 10.1038/s41598-023-36594-3. Sci Rep. 2023. PMID: 37322047 Free PMC article. No abstract available.
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression.
Chen Z, Giotti B, Kaluzova M, Vallcorba MP, Rawat K, Price G, Herting CJ, Pinero G, Cristea S, Ross JL, Ackley J, Maximov V, Szulzewsky F, Thomason W, Marquez-Ropero M, Angione A, Nichols N, Tsankova NM, Michor F, Shayakhmetov DM, Gutmann DH, Tsankov AM, Hambardzumyan D. Chen Z, et al. Among authors: ross jl. J Clin Invest. 2023 Nov 15;133(22):e163802. doi: 10.1172/JCI163802. J Clin Invest. 2023. PMID: 37733448 Free PMC article.
373 results