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Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody.
Leukemia. 2023 Jun;37(6):1349-1360. doi: 10.1038/s41375-023-01883-3. Epub 2023 Apr 6.
Leukemia. 2023.
PMID: 37024520
Discovery and evaluation of a novel monocyclic series of CXCR2 antagonists.
Austin RP, Bennion C, Bonnert RV, Cheema L, Cook AR, Cox RJ, Ebden MR, Gaw A, Grime K, Meghani P, Nicholls D, Phillips C, Smith N, Steele J, Stonehouse JP.
Austin RP, et al. Among authors: stonehouse jp.
Bioorg Med Chem Lett. 2015 Apr 1;25(7):1616-20. doi: 10.1016/j.bmcl.2015.01.067. Epub 2015 Feb 3.
Bioorg Med Chem Lett. 2015.
PMID: 25708618
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Efficient and facile synthesis of acrylamide libraries for protein-guided tethering.
Allen CE, Curran PR, Brearley AS, Boissel V, Sviridenko L, Press NJ, Stonehouse JP, Armstrong A.
Allen CE, et al. Among authors: stonehouse jp.
Org Lett. 2015 Feb 6;17(3):458-60. doi: 10.1021/ol503486t. Epub 2015 Jan 12.
Org Lett. 2015.
PMID: 25582165
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Towards the enantioselective synthesis of (-)-euonyminol--preparation of a fully functionalised lower-rim model.
Webber MJ, Warren SA, Grainger DM, Weston M, Clark S, Woodhead SJ, Powell L, Stokes S, Alanine A, Stonehouse JP, Frampton CS, White AJ, Spivey AC.
Webber MJ, et al. Among authors: stonehouse jp.
Org Biomol Chem. 2013 Apr 21;11(15):2514-33. doi: 10.1039/c3ob27187k. Epub 2013 Feb 26.
Org Biomol Chem. 2013.
PMID: 23443742
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Absolute configuration assignment by asymmetric syntheses of the homalium alkaloids (-)-(R,R,R)-hoprominol and (-)-(4'S,4″R,2‴R)-hopromalinol.
Davies SG, Lee JA, Roberts PM, Stonehouse JP, Thomson JE.
Davies SG, et al. Among authors: stonehouse jp.
J Org Chem. 2012 Nov 2;77(21):9724-37. doi: 10.1021/jo301830j. Epub 2012 Oct 23.
J Org Chem. 2012.
PMID: 23046316
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Asymmetric syntheses of the homalium alkaloids (-)-(S,S)-homaline and (-)-(R,R)-hopromine.
Davies SG, Lee JA, Roberts PM, Stonehouse JP, Thomson JE.
Davies SG, et al. Among authors: stonehouse jp.
J Org Chem. 2012 Aug 17;77(16):7028-45. doi: 10.1021/jo3012732. Epub 2012 Aug 7.
J Org Chem. 2012.
PMID: 22827544
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A practical method for targeted library design balancing lead-like properties with diversity.
Stocks MJ, Wilden GR, Pairaudeau G, Perry MW, Steele J, Stonehouse JP.
Stocks MJ, et al. Among authors: stonehouse jp.
ChemMedChem. 2009 May;4(5):800-8. doi: 10.1002/cmdc.200900050.
ChemMedChem. 2009.
PMID: 19360802
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