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Gene editing to prevent ventricular arrhythmias associated with cardiomyocyte cell therapy.
Marchiano S, Nakamura K, Reinecke H, Neidig L, Lai M, Kadota S, Perbellini F, Yang X, Klaiman JM, Blakely LP, Karbassi E, Fields PA, Fenix AM, Beussman KM, Jayabalu A, Kalucki FA, Potter JC, Futakuchi-Tsuchida A, Weber GJ, Dupras S, Tsuchida H, Pabon L, Wang L, Knollmann BC, Kattman S, Thies RS, Sniadecki N, MacLellan WR, Bertero A, Murry CE. Marchiano S, et al. Among authors: sniadecki n. Cell Stem Cell. 2023 Apr 6;30(4):396-414.e9. doi: 10.1016/j.stem.2023.03.010. Cell Stem Cell. 2023. PMID: 37028405 Free PMC article.
Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes.
Kuppusamy KT, Jones DC, Sperber H, Madan A, Fischer KA, Rodriguez ML, Pabon L, Zhu WZ, Tulloch NL, Yang X, Sniadecki NJ, Laflamme MA, Ruzzo WL, Murry CE, Ruohola-Baker H. Kuppusamy KT, et al. Proc Natl Acad Sci U S A. 2015 May 26;112(21):E2785-94. doi: 10.1073/pnas.1424042112. Epub 2015 May 11. Proc Natl Acad Sci U S A. 2015. PMID: 25964336 Free PMC article.
LAMP-2B regulates human cardiomyocyte function by mediating autophagosome-lysosome fusion.
Chi C, Leonard A, Knight WE, Beussman KM, Zhao Y, Cao Y, Londono P, Aune E, Trembley MA, Small EM, Jeong MY, Walker LA, Xu H, Sniadecki NJ, Taylor MR, Buttrick PM, Song K. Chi C, et al. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):556-565. doi: 10.1073/pnas.1808618116. Epub 2018 Dec 24. Proc Natl Acad Sci U S A. 2019. PMID: 30584088 Free PMC article.
71 results